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Vaccine Detail

MDX-CTLA4 Antibody/Tyrosinase/gp100/MART-1 Melanoma Vaccine
Vaccine Information
  • Vaccine Name: MDX-CTLA4 Antibody/Tyrosinase/gp100/MART-1 Melanoma Vaccine
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Type: Cocktail vaccine
  • Status: Clinical trial
  • Host Species for Licensed Use: None
  • Antigen: tyrosinase 368-376 (370D); gp100 209-217 (210M); and MART-1 26-35 (27L) (NCT00028431)
  • Immunization Route: Intravenous injection (i.v.)
  • Description: This melanoma vaccine chemotherapy cocktail is composed of CTLA-4 antibody; tyrosinase, gp100, and MART-1 peptides; and incomplete Freund's adjuvant (IFA) with or without interleukin-12 in patients with resected stage III or IV melanoma. (NCT00028431)
Host Response
References
NCT00028431: Novel Adjuvants for Peptide-Based Melanoma Vaccines [https://clinicaltrials.gov/study/NCT00028431]