VIOLIN: Vaccine Investigation and Online Information Network

Community Efforts

Vaccine Ontology: A community-based effort to develop the Vaccine Ontology (VO) for vaccine data standardization and automated reasoning. VO is being developed by collaboration with the Ontology for Biomedical Investigations (OBI), the National Center for Biomedical Ontology (NCBO) and the Infectious Disease Ontology (IDO) initiative.

VIOLIN News >>

10/17-19/2011: Oliver attended the 5th Annual Vaccine Renaissance Conference (Vax-Ren-5) at Providence, RI, USA. He presented a talk "Genome-wide vaccine target prediction based on Vaxign reverse vaccinology".
10/2-4/2011: Oliver and Allen presented two posters in the 5th Vaccine and ISV Annual Global Congress in Seattle. Oliver's poster title is "VIOLIN: an integrative vaccine research database and analysis system". Allen's poster title is: "Bioinformatics analysis of protective antigens in manually curated Protegen database".
10/1/2011: Oliver presented a talk "Genome-wide vaccine target prediction using Vaxign reverse vaccinology" in the 1st Computational Vaccinology workshop prior to the 5th Vaccine and ISV Annual Global Congress. Oliver and Allen has also organized a 1.5-hour Vaxign hands-on exercise.
6/20/2011: A comprehensive 26-page review article titled "Emerging Vaccine Informatics" in the Journal of Biomedicine and Biotechnology 2010 special issue on vaccine informatics was published. Oliver is a co-author of this article. This review also introduces VIOLIN and VO.
4/23-25/2011: Oliver presented Vaxign and co-chaired the section "Section 2-2-1: Bioinformatics, Antigen Design, and Vaccine Development" in the BIT 3rd World Vaccine Congress.

Latest Vaccine Publications >>

Surendran N, Hiltbold EM, Heid B, Akira S, Standiford TJ, Sriranganathan N, Boyle SM, Zimmerman KL, Makris MR, Witonsky SG. Role of TLRs in Brucella mediated murine DC activation in vitro and clearance of pulmonary infection in vivo Vaccine 2012 [PMID: 22234268]
Li X, Marinkovic M, Russo C, McKnight CJ, Coetzer TL, Chishti AH. Identification of a specific region of Plasmodium falciparum EBL-1 that binds to host receptor glycophorin B and inhibits merozoite invasion in human red blood cells Molecular and biochemical parasitology 2012 [PMID: 22273481]

Vaccine News >>

Roswell Park's Cancer Vaccine Uses Body's Own Immunity in Trial
ThirdAge Jan 27, 2012 17:10
Oral Cancer: Another target ripe for HPV vaccine
American Council on Science and Health Jan 27, 2012 16:52
More Evidence Your Guy Needs The HPV Vaccine, Too
Cosmopolitan Jan 27, 2012 16:47

Statistics: The VIOLIN vaccine database contains 2933 vaccines or vaccine candidates for 175 pathogens by manual curation from 1662 peer-reviewed papers. It also contains 24,345 vaccine-related abstracts and 10,317 full text documents.

Please cite this publication: Zuoshuang Xiang, Thomas Todd, Kim P. Ku, Bethany L. Kovacic, Charles B. Larson, Fang Chen, Andrew P. Hodges, Yuying Tian, Elizabeth A. Olenzek, Boyang Zhao, Lesley A. Colby, Howard G. Rush, Janet R. Gilsdorf, George W. Jourdian, Yongqun He. VIOLIN: Vaccine Investigation and Online Information Network. Nucleic Acids Res. 2008 Jan;36(Database issue):D923-8. [NAR] [PubMed] [PDF].

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