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yscF

General Information
Protegen ID 100
Sequence Strain (Species/Organism) Yersinia pestis CO92
VO ID VO_0010914
Taxonomy ID 214092
Other Database IDs CDD:131160
Molecule Role Protective antigen
Molecule Role Annotation The P4 protein is an integral outer membrane protein that has a role in acquiring hemin and nucleosides (Green et al., 1991).
Related Vaccines(s) Non-typeable H. influenzae rLP4/rLP6 and Moraxella catarrhalis UspA2 protein vaccine
References
Green et al., 1991: Green BA, Farley JE, Quinn-Dey T, Deich RA, Zlotnick GW. The e (P4) outer membrane protein of Haemophilus influenzae: biologic activity of anti-e serum and cloning and sequencing of the structural gene. Infection and immunity. 1991 Sep; 59(9); 3191-8. [PubMed: 1715322 ].
Gene Information
Gene Name yscF
Genbank Accession AL117189
Locus Tag YPCD1.55
Gene Starting Position 41025
Gene Ending Position 41288
DNA Sequence 
>NC_003131.1:41025-41288 Yersinia pestis CO92 plasmid pCD1, complete sequence
AATGAGTAACTTCTCTGGATTTACGAAAGGAACCGATATCGCAGACTTAGATGCGGTGGCTCAAACGCTC
AAGAAGCCAGCAGACGATGCAAACAAAGCGGTTAATGACTCGATAGCAGCATTGAAAGATAAGCCTGACA
ACCCGGCGCTACTTGCTGACTTACAACATTCAATTAATAAATGGTCGGTAATTTACAATATAAACTCAAC
CATAGTTCGTAGCATGAAAGACTTAATGCAAGGCATCCTACAGAAGTTCCCATA
Protein Information
Protein Name needle complex major subunit
NCBI Protein GI 16082743
Protein Accession NP_395189
3D structure: PDB ID 3ET4
Protein pI 7.35
Protein Weight 9570.09
Protein Length 165
Protein Note type III secretion apparatus needle protein; TIGR02105
Protein Sequence 
>NP_395189.1 needle complex major subunit (plasmid) [Yersinia pestis CO92]
MSNFSGFTKGTDIADLDAVAQTLKKPADDANKAVNDSIAALKDKPDNPALLADLQHSINKWSVIYNINST
IVRSMKDLMQGILQKFP
Epitope Information
IEDB Linear Epitope