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Rv2660c

General Information
Protegen ID 1064
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
Taxonomy ID 83332
Molecule Role Protective antigen
Molecule Role Annotation When combined with AG85B and ESAT-6, Rv2660c provided mice protection against challenge (Aagaard et al., 2011).
References
Aagaard et al., 2011: Aagaard C, Hoang T, Dietrich J, Cardona PJ, Izzo A, Dolganov G, Schoolnik GK, Cassidy JP, Billeskov R, Andersen P. A multistage tuberculosis vaccine that confers efficient protection before and after exposure. Nature medicine. 2011; 17(2); 189-194. [PubMed: 21258338].
Gene Information
Gene Name Rv2660c
NCBI Gene ID 887222
Genbank Accession CP009480
Locus Tag Rv2660c
Gene Starting Position 2980962
Gene Ending Position 2981189
DNA Sequence 
>NC_000962.3:2980962-2981189 Mycobacterium tuberculosis H37Rv, complete genome
ACTAGTGAAACTGGTTCAATCCCAGTATCGCGCACCACGATTGACCTGCGGTTTCATCCACAAAATCTGG
GCTGCGTGAACTAAATGTGAACTGACTCGGTGCAACCACCGAAAGGTTCCTCTGTTCCGTGCCCACGCCG
ACACCGACGGTGACCCCACCAGATGCGCCTGCCGCCCGCTGGCTAGCCTGGCCTGTTGCTGCAAGCGCCT
GGTCGACGCCCGCTATCA
Protein Information
Protein Name hypothetical protein
NCBI Protein GI 15609797
Protein Accession NP_217176
Protein pI 4.63
Protein Weight 6788.85
Protein Length 75
Protein Note Rv2660c, (MTCY441.29c), len: 75 aa (questionable orf). Hypothetical unknown protein.
Protein Sequence 
>NP_217176.1 hypothetical protein Rv2660c [Mycobacterium tuberculosis H37Rv]
MIAGVDQALAATGQASQRAAGASGGVTVGVGVGTEQRNLSVVAPSQFTFSSRSPDFVDETAGQSWCAILG
LNQFH
Vaxign Prediction
Localization(Probability) Unknown
(Prob.=0.25)
Adhesin Probability 0.589
Trans-membrane Helices 0
Detailed Vaxign Results Vaxign Results
Epitope Information
IEDB Linear Epitope