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Muc1

General Information
Protegen ID 1340
Sequence Strain (Species/Organism) Mus musculus
Taxonomy ID 10090
Molecule Role Protective antigen
Related Vaccines(s) Lung metastasis DNA vaccine pCEP4-MUC1 encoding MUC1 , MUC1-FSL-1-TT tricomponent vaccine
References  
Gene Information
Gene Name Muc1
NCBI Gene ID 17829
Genbank Accession AC132327
Chromosome No 3
Gene Starting Position 89229055
Gene Ending Position 89233380
DNA Sequence 
>NC_000069.6:89229055-89233380 Mus musculus strain C57BL/6J chromosome 3, GRCm38.p4 C57BL/6J
CCTCACACACGGAGCGCCAGCCTTGAGTTTGTTTTCTAGCCCCTTCCCGCCTGTTCACCACCACCATGAC
CCCGGGCATTCGGGCTCCTTTCTTCCTGCTGCTACTTCTAGCAAGTCTAAAAGGTGAGAGGCGCAAGGTG
GGGAGGGGCTGCGCTGTTCAGGTGGGACTCCCAGTCTTTCTGTGGAGTTTGCTTACTGGTAGATTATGAG
AGTCATAAATGGCCATCCATACAGGTATGGCCCAGTATGTGCCAGGGGGGAAAAGAGGCTAAGGAAGGAG
GCTGAGAAGAGGTGACCCCTCAGGAGAGTGGGCACTATAGTAGGCAAATAATACTCTTTGTGGGGAGTAG
AGAAGAGAGGCTGTGTCAGGAGAAGTAGCTCCGGAGTGGAAGAATGGGGCCGTGTGCAGTGGTTCCAGTC
TATAGTTCCCACACCCTGGACGCTCAGGTTCACAGAGAGTTCAAGGCCAGCTTAGGCTACAGTATGAATA
CTTGTCTCAAGTAGAGGAATAAATGAGCCAGAAGCAGAGGTGAGACCTCTGCTTAGGGAGGGAGGCTGTC
AGGATGAAGGCAAACCAGGGGCTACCTGATGCTAACATGATCCCCCTTCCTTCCCCGGTTACTTTGTTTT
CAGAGTTTATATTTTTCTTCTTGCTCTGATTTTTATTCATCAACCCAGTAGGTTTTTTTTTTGTTGTTGT
TGTTGTTTTGTTTTTTTTTTCTTCAACTTTGGCTCTAGCCGGAACTAAAACATCACACATGTTATCCAAA
GCGACCCAGTGTCCAACTCTGTTGATTAGTGCTGCGCTGCTGTGAGCATAAAAACAGTTTACCCCTAATC
TTCCACTCTGGTTCAGGTTTTCTTGCCCTTCCAAGTGAGGAAAACAGTGTCACCTCATCTCAGGACACCA
GCAGTTCCTTAGCATCGACTACCACTCCAGTCCACAGCAGCAACTCAGACCCAGCCACCAGACCTCCAGG
GGACTCCACCAGCTCTCCAGTCCAGAGTAGCACCTCTTCTCCAGCCACCAGAGCTCCTGAAGACTCTACC
AGTACTGCAGTCCTCAGTGGCACCTCCTCCCCAGCCACCACAGCTCCAGTGAACTCCGCCAGCTCTCCAG
TAGCCCATGGTGACACCTCTTCCCCAGCCACTAGCCTTTCAAAAGACTCCAACAGCTCTCCAGTAGTCCA
CAGTGGCACCTCTTCAGCTCCGGCCACCACAGCTCCAGTGGATTCCACCAGCTCTCCAGTAGTCCACGGT
GGTACCTCGTCCCCAGCCACCAGCCCTCCAGGGGACTCCACCAGCTCTCCAGACCATAGTAGCACCTCTT
CTCCAGCCACCAGAGCTCCCGAAGACTCTACCAGTACTGCAGTCCTCAGTGGCACCTCCTCCCCAGCCAC
CACAGCTCCAGTGGACTCCACCAGCTCTCCAGTAGCCCATGATGACACCTCTTCCCCAGCCACTAGCCTT
TCAGAAGACTCCGCCAGCTCTCCAGTAGCCCACGGTGGCACCTCTTCTCCAGCCACCAGCCCTCTAAGGG
ACTCCACCAGTTCTCCAGTCCACAGTAGTGCCTCCATCCAAAACATCAAGACTACATCAGACTTAGCTAG
CACTCCAGACCACAATGGCACCTCAGTCACAACTACCAGCTCTGCACTGGGCTCAGCCACCAGTCCAGAC
CACAGTGGTACCTCAACTACAACTAACAGCTCTGAATCAGTCTTGGCCACCACTCCAGTTTACAGTAGCA
TGCCATTCTCTACTACCAAAGTGACGTCAGGCTCAGCTATCATTCCAGACCACAATGGCTCCTCGGTGCT
ACCTACCAGTTCTGTGTTGGGCTCAGCTACCAGTCTAGTCTATAATACCTCTGCAATAGCTACAACTCCA
GTCAGCAATGGCACTCAGCCTTCAGTGCCAAGTCAATACCCTGTTTCTCCTACCATGGCCACCACCTCCA
GCCACAGCACTATTGCCAGCAGCTCTTACTATAGCACAGTACCATTTTCTACCTTCTCCAGTAACAGTTC
ACCCCAGTTGTCTGTTGGGGTCTCCTTCTTCTTCTTGTCTTTTTACATTCAAAACCACCCATTTAATTCT
TCTCTGGAAGACCCCAGCTCCAACTACTACCAAGAACTGAAGAGGAACATTTCTGGATTGGTGGGTATCA
GCCTAGCCTCTGCCATGTGTCCCCTGACGTAGCTCTTCAGGACTGCATGGCTTTCACATCACTCCTGAGT
CTTCTCCTCTTCTCCCAGTTTCTGCAGATTTTTAACGGAGATTTTCTGGGGATCTCTAGCATCAAGTTCA
GGTACAGTTCTGGATTTGACTTGGGGGAGGAATGGTCAGTCTCGTGACTTTGTGGTGTCGGGATGGGGGT
GGGGTGGGGAGAGGAGTGCTGAGCTATAAGCTCAGTCTATCTGAGCTCCCTATTTCCTGTGACCAGGTCA
GGCTCCGTGGTGGTAGAATCGACTGTGGTTTTCCGGGAGGGTACTTTTAGTGCCTCTGACGTGAAGTCAC
AGCTTATACAGCATAAGAAGGAGGCAGATGACTATAATCTGACTATTTCAGAAGTCAAAGGTGAGGTGAT
AGCCCCAGCTGCAGCCTGGCACCATACTATGGGGCTTTACCACCTGTTTACTTCTGGCGCCAGGAGTGGG
AAATCCACCTCCCTTGGGGACTTCCCTGACCACCGCTTTCCCTTCTAGTGAATGAGATGCAGTTCCCTCC
CTCTGCCCAGTCCCGGCCGGGGGTACCAGGCTGGGGCATTGCCCTGCTGGTGCTGGTCTGTATTTTGGTT
GCTTTGGCTATCGTCTATTTCCTTGCCCTGGTAAGTCTCAAGCCTTCTGCGGCGCGGTGTGCCCTTGGTA
AATGGAACCCCACTGGCCAATCCAATCTCCTGTCTCCCTAGGCAGTGTGCCAGTGCCGCCGAAAGAGCTA
TGGGCAGCTGGACATCTTTCCAACCCAGGACACCTACCATCCTATGAGTGAATACCCTACCTACCACACT
CACGGACGCTACGTGCCCCCTGGCAGTACCAAGCGTAGCCCCTATGAGGAGGTAAAGTGTATCCCGAAGA
AGCTTGGGCCATCGACCTGGGCAGGGTGGGGCCTTCTGAAGGGGAACTTGGGAAAAACCCAAGGAAGCCC
AGATAGGTGAGCAGTTGGAGCCTGGCAAGGTTGGGAATGGAGGTCGAGTTCTGGGGGCGGGGGGAGGGGG
TCAGACCTTGGGAGATGACAGAAAAAAGTGTCTGCACTACCAGTCTTCCCCAAAAAGCCTCGCCGTCTAC
CTGTACCATTCTGTACTCATTAGGATGCCCAGAGGTGAGGCTAGGAGATCCTGTGCCCCTGGGAGCCCCG
CCCACTGCATTTCCCGCTGACCTCCTAGGGGTCTGGGAGTAGATACATGGGGCTGGGGTAGGGTGGGAGG
GCTCTGATGGAAGAGAAGTTTCCTCTTGCTAGATGAGTGTGCTGAGGGAGTTTTAGGAAAGCAAGGGTAC
CTCTCTCTTCCCTCCCTCAGGCCTTTCCCTGTTGAGTCTCGTAAATAATTACTGTGGCCACCTGAGACCG
AAAGGCCAGTGGGTGGGGAAGGAGACAAGCACGTCCTTTTCTCGCCCCACTTTCCTCCTCCTCCAGATAC
ACACACACACACACAAACACACACACACACACACACACACACACACACACACACACACAGCCCTTTGGGC
CAGAGGATCAAAAACTAAAAGGAGAGAAAGATAGGTGGGGCCTACAAGAGGGCTAGGGATCTACAGCCAA
GCGGAGGGGAGTGTGGGGGGGGAGGGGGCAGTGGAGTTGTGTGTTTACAGTCACCTGGCAGCTCTGGGGC
CAGCAGGTGCACACTCCGAATTAACCCCTTGAGAGCTTGCCAGGCCCCTTGGCCCCAGGTGCCATCGGGG
TTTTACCTGGAAGATTCTTTTTCCCTGAAATTATTTCCCCTTCACTCAGGTTTCGGCAGGTAATGGCAGT
AGCAGTCTCTCTTATACCAACCCAGCTGTGGTGACCACTTCTGCCAACTTGTAGGAGCAAGTCACCCCAC
CCACTTGGGGCAGCTTTGGCGGTCTGCTCCCTCAGTGGTCACTGCCAGACCCCTGCACTCTGATCTGGGC
TGGTGAGCCAGGACTTCTGGTAGGCTGTTCATGCCCTTTGTCAAGCGCCTCAACTACGTAAGCCTGGTGA
AGCCCAGCCCTGCCCTGGGGGACACTGGGGCAGTTAGTGGTGGCTCTCAGAAGGACTGGCCTGGAAAACT
GGAGACAGGGATGGGAACCCAAACATAGCTGAATAAAAGATGGCCTCCTGTTAGTT
Protein Information
Protein Name mucin 1, transmembrane
NCBI Protein GI 7305293
Protein Accession NP_038633
Protein pI 5.45
Protein Weight 59972.84
Protein Length 631
Protein Note Also known as EMA; CD227; Muc-1
Protein Sequence 
>NP_038633.1 mucin-1 precursor [Mus musculus]
MTPGIRAPFFLLLLLASLKGFLALPSEENSVTSSQDTSSSLASTTTPVHSSNSDPATRPPGDSTSSPVQS
STSSPATRAPEDSTSTAVLSGTSSPATTAPVNSASSPVAHGDTSSPATSLSKDSNSSPVVHSGTSSAPAT
TAPVDSTSSPVVHGGTSSPATSPPGDSTSSPDHSSTSSPATRAPEDSTSTAVLSGTSSPATTAPVDSTSS
PVAHDDTSSPATSLSEDSASSPVAHGGTSSPATSPLRDSTSSPVHSSASIQNIKTTSDLASTPDHNGTSV
TTTSSALGSATSPDHSGTSTTTNSSESVLATTPVYSSMPFSTTKVTSGSAIIPDHNGSSVLPTSSVLGSA
TSLVYNTSAIATTPVSNGTQPSVPSQYPVSPTMATTSSHSTIASSSYYSTVPFSTFSSNSSPQLSVGVSF
FFLSFYIQNHPFNSSLEDPSSNYYQELKRNISGLFLQIFNGDFLGISSIKFRSGSVVVESTVVFREGTFS
ASDVKSQLIQHKKEADDYNLTISEVKVNEMQFPPSAQSRPGVPGWGIALLVLVCILVALAIVYFLALAVC
QCRRKSYGQLDIFPTQDTYHPMSEYPTYHTHGRYVPPGSTKRSPYEEVSAGNGSSSLSYTNPAVVTTSAN
L
Epitope Information
IEDB Linear Epitope