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ROP8

General Information
Protegen ID 1635
Sequence Strain (Species/Organism) Toxoplasma gondii
Taxonomy ID 5811
Other Database IDs CDD:291215
CDD:304357
Molecule Role Protective antigen
Related Vaccines(s) T. gondii DNA vaccine encoding multi-epitope ROP8 , T. gondii DNA vaccine ROP8-pVAX-1
References  
Gene Information
Gene Name ROP8
NCBI Gene ID 7897075
NCBI Nucleotide GI 2293518
DNA Sequence 
>gi|2293518|gb|AF011377.1| Toxoplasma gondii rhoptry antigen ROP8 gene, complete cds
GAATTCGCTAGTCTCAGGTCGAGTCGCCGGGGCGTCAGGAGACAAGCACCGGCGCCCCGCGCGCCAACTG
TCCGTCCTTCCGGGTGAGTTGACGTTTTGAGCCACGCTGCAGAACTCTGCACTGGAGTGATTGAGCGCGG
CATTTATGTCAATCTGGTTTTTCCACGTGTATTCCAGAAGCTTGCCCTGAGAAATACAGATACACTGTCA
CTTTTGAATCGATGTTTTCTGTGTTACGTAACCGCAACATGAGACACGGTCCCTCGATTGGATCGTCATC
ATGTCTTATCTGGCTAGCTGCCGCATTCTTTGTTTCGGCACTTGGCCACGTACAGCAAGGCGCTGGCGTT
GTGCGGCCTCGCCACTGGCAGAACTCGGAAGCCGCTGTTAGTGTCCGGTCGCCGGGAGGCGCGTCCCCTA
GACATTTCCACAGCCCAATTGAGCCAGTAGCATTTATTGATGGGGAGCACGATGAAGACAAGCATGAAGG
CTCATGGTTGGAGCAGGAAGCGGCCGAGGATGTGACCCCTTTACCGGGCAGCCACACAGAGGCCCAGACA
CAGTCCCCCAGTGCTTTTAGAAGGTTAACCAGGCGTTTGCGTTTTTGGCGACGTGGGGTGACAGGCGGAT
CAGATGCTGGAGAAGAGGCGCCTCAGACGCCTCGACCTCCACTACGTACACGAATCCTTCAGTACTTGCG
GCGTGTGGGAACATTTTTCAGACGAGACATTCCAGCGGCAGCACTTCGATTCTTCAGGCGCTTTCGACGA
GTCCGCCAACCTGTATTCCCTCCCGACGAGTTTCCGGAGGATGTCGACACGAACCCTATTTATTTCCGTG
GTACGGATCCTGGAGACGTTGTCATTGAGGAGCTGTTCAATCGTATACCGCAAGCAAACGTACGGACTAC
AAGTGATTACATGCAGTCCGCAGCTGACAGTCTAGTGTCCACATCGTTGTGGAATATTGGACAGCCCTTC
CGCGTAGAGTCGGAGCTTGGCGAGCGTCCAAGGACGCTAGTCAGGGGCACATTGCTCGGCCAGGAAGACC
CTTATGCCTATGTCGAGGCGACCGACCAGGAGACAGGAGAATCATTTGAGGTGCACGTTCCACTTTCCAA
GGAAAAGCCGTCTTCCAACACGATCAAGCAGATGAAGCAGGAGGTGCTGCGCCTACGCTTGCTACGAGGC
ATCAAAAACCAGAAGCAAGCCAAGGTGCATCTCAGATTTATATTCCCCTTCGATTTGGTGAAGGACCCAC
AGAAAAAGAAGATGATCCAGGGTGTCTCAGATGAGGGGGCTGGCTGGATCGTGAACGGATTCTTTCTGTA
TCCCCGAATGCAGACTAACCTTCAGACGCTTGGAGAAGTCCTACTGAGTCATTCCTCAACACACAAGTCC
CTCGTGCACCACGCTCGGTTGCAGCTCACGCTTCAGGTCATAAGGCTGCTTGCGGGTCTCCACCACTATG
GCCTTGTGCATACCTTTTTTAGGGCCGTCGATATCGTCTTGGACCAGCGTGGTGGCGTGTTTTTGACCGG
CTTTGAACATCTGGTGCGAGACGGCGACAGGGTGGTGTCGACCGTCTGTCGAGGATTCGAACCGCCGGAG
CTTGAAGCCAGACGAGCAACCATATCTTACCACAGGGACCGCAGGACGCTGATGACATTTTCGTTTGATG
CATGGGCATTGGGGTTGGTGATCTACTGGATTTGGTGCGCCGATTTGCCCAATACCAAGGACGCGCCGCT
AGGCGGAAGTGACTGGATCTTTCGACGCTGCAAGAATATCCCACAGCCAGTCAGAGCTTTGCTTGCGGGA
TTCTTGCGATACCCGCAAGAGAATCGGCTCCTSCCATTGCAAGCCATGGAGACTCCTGAGTACGAGCAAC
TGCGCACAGAGCTATCAGCCGTTTTGCCCCTGTATCTTTCTGATGGAGAACCGGCATGAGAGGGTGGCGC
GCCACCATCGGGAACATCTCAGCCGGACGAAGCTGGAGTCGCTGAGGCGGTTACGGCAATCTAGAACCTC
GAGGAGGGGCCAGCGATGAGCTTGAATTC
Protein Information
Protein Name ROP8
NCBI Protein GI 2293519
Protein Accession AAC47797.1
Protein pI 9.42
Protein Weight 61810.69
Protein Length 622
Protein Note Kinase-like; pfam14531
Protein Sequence 
>AAC47797.1 ROP8 [Toxoplasma gondii]
MFSVLRNRNMRHGPSIGSSSCLIWLAAAFFVSALGHVQQGAGVVRPRHWQNSEAAVSVRSPGGASPRHFH
SPIEPVAFIDGEHDEDKHEGSWLEQEAAEDVTPLPGSHTEAQTQSPSAFRRLTRRLRFWRRGVTGGSDAG
EEAPQTPRPPLRTRILQYLRRVGTFFRRDIPAAALRFFRRFRRVRQPVFPPDEFPEDVDTNPIYFRGTDP
GDVVIEELFNRIPQANVRTTSDYMQSAADSLVSTSLWNIGQPFRVESELGERPRTLVRGTLLGQEDPYAY
VEATDQETGESFEVHVPLSKEKPSSNTIKQMKQEVLRLRLLRGIKNQKQAKVHLRFIFPFDLVKDPQKKK
MIQGVSDEGAGWIVNGFFLYPRMQTNLQTLGEVLLSHSSTHKSLVHHARLQLTLQVIRLLAGLHHYGLVH
TFFRAVDIVLDQRGGVFLTGFEHLVRDGDRVVSTVCRGFEPPELEARRATISYHRDRRTLMTFSFDAWAL
GLVIYWIWCADLPNTKDAPLGGSDWIFRRCKNIPQPVRALLAGFLRYPQENRLLPLQAMETPEYEQLRTE
LSAVLPLYLSDGEPA
Epitope Information
IEDB Linear Epitope