VIOLIN: Vaccine Investigation and Online Information Network

S

General Information

Protegen ID

1705

Sequence Strain (Species/Organism)

Duck hepatitis B virus isolate CH6

Taxonomy ID

12639

Other Database IDs

CDD:279085

Molecule Role

Protective antigen

Related Vaccines(s)

Hepatitis B virus DNA vaccine encoding HBVgp2 pre-S1/pre-S2/S

References

Gene Information

Gene Name

Protein Information

Protein Name

large S protein

NCBI Protein GI

169116569

Protein pI

8.31

Protein Weight

39801.32

Protein Length

427

Protein Note

Major surface antigen from hepadnavirus; pfam00695

Protein Sequence

>ACA42588.1 large S protein [Duck hepatitis B virus]
MKQESFISGYLNIWSHLKVSLIIGNSNTLSINITFMMGQHPAKSMDVRRIEGGEILLNQLAGRMIPKGTL
TWSGKFPTLDHVLDHVQTMEEINTLQNQGAWPAGAGRRVGLSNPTPQEIPQPQWTPEEDQKAREAFRRYQ
EERPPETTTIPPSSPPQWKLQPGDDPLLGNQSLLETHPLYQYTEPEPAVPVIKTPPLKKKMSGTFGGILA
GLIGLLVSFFLLIKILEILRRLDWWWISLSSPKGKMQCAFQDTGAQISPHYVGSCPWGCPGFLWTYLRLF
IIFLLILLVAAGLLYLTDNGSTILGKLQWASVSALFSSISSLLPSDPKSLVALTFGLSLIWMTSSSATQT
LVTLTQLVTLSALFYKS

Epitope Information

IEDB Linear Epitope

IEDB ID	Epitope	Starting position	Ending position
41610	MGQHPAKSMDVRR	37	50
37354	LLGNQSLL	167	175
9669	DPLLGNQS	165	173
61282	SSPPQWKL	153	161
50836	QGAWPAGA	98	106
68725	VGLSNPTP	109	117
20564	GKFPTLDH	74	82
41350	MEEINTLQ	89	97
17427	FPTLDHVL	76	84
37227	LLETHPLY	173	181
65114	TLTWSGKF	69	77
45628	NQSLLETH	170	178
48073	PKGTLTWS	66	74
59650	SMDVRRIE	44	52
33436	KSMDVRRI	43	51
22753	GTLTWSGK	68	76
69412	VLDHVQTM	82	90
38321	LNQLAGRM	57	65
27185	ILLNQLAG	55	63
47262	PEEDQKAR	126	134
75475	YQEERPPE	139	147
21131	GLSNPTPQ	110	118
45556	NQGAWPAG	97	105
67297	TWSGKFPT	71	79
29926	KAREAFRR	131	139
55783	RRYQEERP	137	145
47442	PETTTIPP	145	153
27997	IPQPQWTP	119	127
11423	EDQKAREA	128	136
55760	RRVGLSNP	107	115
51751	QNQGAWPA	96	104
55609	RRIEGGEILLNQLAGRMIP	48	67
48926	PPSSPPQW	151	159
60190	SPPQWKLQ	154	162
50580	QEERPPET	140	148
66856	TTTIPPSS	147	155
49513	PSSPPQWK	152	160
72688	WKLQPGDD	158	166
70654	VQTMEEIN	86	94
22199	GRRVGLSN	106	114
49745	PTPQEIPQ	114	122
31074	KGTLTWSG	67	75
17642	FRRYQEER	136	144
49072	PQPQWTPE	120	128
49691	PTLDHVLDHVQT	77	89
22149	GRMIPKGT	62	70
73074	WSGKFPTL	72	80
64752	TLDHVLDH	78	86
51019	QHPAKSMD	39	47
19715	GGEILLNQ	52	60
65541	TPEEDQKA	125	133
52572	QTMEEINT	87	95
65193	TMEEINTL	88	96
48990	PQEIPQPQ	116	124
66659	TTIPPSSPP	148	157
18954	GDDPLLGNQ	163	172
51943	QPQWTPEE	121	129
52863	QWTPEEDQ	123	131
73151	WTPEEDQK	124	132
65704	TPQEIPQP	115	123
11692	EEINTLQN	90	98
27748	INTLQNQG	92	100
46165	NTLQNQGA	93	101
18607	GAGRRVGL	104	112
1671	AGRRVGLS	105	113
35176	LDHVQTME	83	91
8580	DHVQTMEE	84	92
25080	HVQTMEEI	85	93
25060	HVLDHVQT	81	89
12550	EIPQPQWT	118	126
35175	LDHVLDHV	79	87
5685	AWPAGAGR	100	108
56300	RVGLSNPT	108	116
46801	PAGAGRRV	102	110
1437	AGAGRRVG	103	111
59880	SNPTPQEI	112	120
45496	NPTPQEIP	113	121
51168	QKAREAFR	130	138
65026	TLQNQGAW	94	102
38923	LQNQGAWP	95	103
18838	GAWPAGAG	99	107
58101	SGKFPTLD	73	81
30821	KFPTLDHV	75	83
49690	PTLDHVLD	77	85
41759	MIPKGTLT	64	72
27896	IPKGTLTW	65	73
9856	DQKAREAF	129	137
55608	RRIEGGEI	48	56
19301	GEILLNQL	53	61
12507	EILLNQLA	54	62
37626	LLNQLAGR	56	64
54140	RIEGGEIL	49	57
34792	LAGRMIPK	60	68
25816	IEGGEILL	50	58
40236	LTWSGKFP	70	78
12171	EGGEILLN	51	59
24425	HPAKSMDV	40	48
46844	PAKSMDVR	41	49
41284	MDVRRIEG	45	53
70812	VRRIEGGE	47	55
51283	QLAGRMIP	59	67
41609	MGQHPAKS	37	45
21883	GQHPAKSM	38	46
45573	NQLAGRMIP	58	67
48771	PPETTTIP	144	152
48396	PLLGNQSL	166	174
36230	LGNQSLLE	168	176
52369	QSLLETHP	171	179
59252	SLLETHPL	172	180
18953	GDDPLLGN	163	171
7846	DDPLLGNQ	164	172
32116	KLQPGDDPLLG	159	170
66658	TTIPPSSP	148	156
47628	PGDDPLLG	162	170
38945	LQPGDDPL	160	168
55248	RPPETTTI	143	151
56627	RYQEERPP	138	146
14053	ERPPETTT	142	150
11560	EEDQKARE	127	135
32115	KLQPGDDP	159	167
4134	AREAFRRY	132	140
53449	REAFRRYQ	133	141
11046	EAFRRYQE	134	142
1391	AFRRYQEE	135	143
64418	TIPPSSPP	149	157
27985	IPPSSPPQ	150	158
48900	PPQWKLQP	155	163
49151	PQWKLQPG	156	164
21504	GNQSLLET	169	177
35723	LETHPLYQ	174	182
55761	RRVGLSNPT	107	116
12537	EINTLQNQ	91	99
1666	AGRMIPKG	61	69
8579	DHVLDHVQ	80	88
52844	QWKLQPGD	157	165
51834	QPGDDPLL	161	169
72924	WPAGAGRR	101	109
39517	LSNPTPQE	111	119
50621	QEIPQPQW	117	125
49153	PQWTPEED	122	130
10714	DVRRIEGG	46	54
54906	RMIPKGTL	63	71
14576	ETTTIPPS	146	154
12551	EIPQPQWTPEEDQK	118	132
45497	NPTPQEIPQPQWTPEEDQKAREAF	113	137
14397	ETHPLYQ	175	182
11561	EEDQKAREA	127	136
18955	GDDPLLGNQSLL	163	175
65027	TLQNQGAWP	94	103
49746	PTPQEIPQPQWTPEEDQKAREAF	114	137
2285	AKSMDVRR	42	50
11862	EERPPETT	141	149
167791	PPQWKLQPG	155	164
167806	QWKLQPGDD	157	166
167770	KLQPGDDPL	159	168
167799	QPGDDPLLG	161	170
167734	EERPPETTT	141	150
167813	RPPETTTIP	143	152
167821	TIPPSSPPQ	149	158
167792	PPSSPPQWK	151	160
167790	PETTTIPPS	145	154
167827	TTTIPPSSP	147	156
167818	SSPPQWKLQ	153	162
167733	DQKAREAFR	129	138
167765	KAREAFRRY	131	140
167809	REAFRRYQE	133	142
167720	AFRRYQEER	135	144
167814	RRYQEERPP	137	146
167832	YQEERPPET	139	148
167825	TPQEIPQPQ	115	124
167795	QEIPQPQWT	117	126
167761	IPQPQWTPE	119	128
167802	QPQWTPEED	121	130
167807	QWTPEEDQK	123	132
167824	TPEEDQKAR	125	134
167742	GAWPAGAGR	99	108
167831	WPAGAGRRV	101	110
167721	AGAGRRVGL	103	112
167723	AGRRVGLSN	105	114
167829	VGLSNPTPQ	109	118
167779	LSNPTPQEI	111	120
167786	NPTPQEIPQ	113	122
167805	QTMEEINTL	87	96
167784	MEEINTLQN	89	98
167788	NTLQNQGAW	93	102
167778	LQNQGAWPA	95	104
167738	EINTLQNQG	91	100
167787	NQGAWPAGA	97	106
167815	SGKFPTLDH	73	82
167767	KFPTLDHVL	75	84
167793	PTLDHVLDH	77	86
167772	LDHVLDHVQ	79	88
167752	HVLDHVQTM	81	90
167773	LDHVQTMEE	83	92
167754	HVQTMEEIN	85	94
167760	IPKGTLTWS	65	74
167798	QLAGRMIPK	59	68
167722	AGRMIPKGT	61	70
167812	RMIPKGTLT	63	72
167768	KGTLTWSGK	67	76
167822	TLTWSGKFP	69	78
167828	TWSGKFPTL	71	80
167783	MDVRRIEGG	45	54
167830	VRRIEGGEI	47	56
167811	RIEGGEILL	49	58
167737	EGGEILLNQ	51	60
167743	GEILLNQLA	53	62
167757	ILLNQLAGR	55	64
167777	LNQLAGRMI	57	66
167775	LLETHPLYQ	173	182
167785	MGQHPAKSM	37	46
167797	QHPAKSMDV	39	48
167789	PAKSMDVRR	41	50
167771	KSMDVRRIE	43	52
167739	EPAVPVIKT	186	195
167726	AVPVIKTPP	188	197
167794	PVIKTPPLK	190	199
167756	IKTPPLKKK	192	201
167804	QSLLETHPL	171	180
167731	DPLLGNQSL	165	174
167776	LLGNQSLLE	167	176
167746	GNQSLLETH	169	178