calpain |
| General Information |
| Protegen ID |
1734 |
|
Sequence Strain (Species/Organism) |
Schistosoma mansoni strain Puerto Rico |
|
Taxonomy ID |
6183
|
|
Other Database IDs |
CDD:279042
CDD:238004
CDD:279416
CDD:238132
CDD:290234
CDD:238008 |
|
Molecule Role |
Protective antigen |
| Related Vaccines(s) |
S. mansoni DNA vaccine Sm-p80-pcDNA3 encoding the large subunit of S. mansoni calpain
|
| References |
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| Gene Information |
|
Gene Name |
calpain |
| Protein Information |
|
Protein Name |
calpain (C02 family) |
|
NCBI Protein GI |
353230291
|
|
Protein pI |
6.64 |
|
Protein Weight |
164811.89 |
|
Protein Length |
1591 |
|
Protein Note |
Calpain family cysteine protease; pfam00648 |
|
Protein Sequence |
>CCD76462.1 calpain (C02 family) [Schistosoma mansoni]
MRRKKQNSDSETECNGVPLNYLDILKPTLTEKRVQFNLNIPCSITPKGYAKLHEKLTSPCIPHSKGKADS
MADRVYRQIFLYCTNSLNGFTHSSKSETTYASPTAMRKIKISQYEIISAKMVEAKELYQDPEFPANDASI
GNLPHVSGRVEWKRPKDINPLAAFCTKSYSRFDVDQGALGDCWFASVMATVTKYPSLMSNIIPPNQTFKG
SGYTGAFVFNFWRFGEWVEVVVDDRIPVVKGTCNPVFIHSTDNSEFWSCLLEKAYAKLCGSYAHLTGGFQ
SEAMEDFTGGICTTLILNKKERPPNLLKMMEHYTKTCCVMGADVGGDKNKRREELGLIGSHAYSVTGVGK
VNYMGKDVYLVRCRNPWGERHEWKGPWSDNSPEWKDVKSKDKRALQYKPKEDGEFCSFQLTFILFISTSI
SRRNVLFGLPLFRFPSPFQVRACLVMQFGDFLNVCPIHFQQSFCTNPQYLFTIGTDNSGKVGKAHIIVGV
MQEHRRFLYGGEYLAIGFSIFEVSELQNTRLTPEELLCRKPLLTSDYIPRREVTLEADLFPGTFILIPST
YNSNQEARYICRVFSTVKMKQLELDEENSYEGFPKKELASLELNFKQLCNPVTEKINSRILGTILDQSNF
GEYMDGFTEFPSNLCSSLISSASTNLTGQIDLEEYLYLLIDLKGWMLTFNKYDDRKGCVSWFKFRDLLKS
SGYKVSNRVFSVLAHRHIDHKRGHISLESYLHCMANLKFAFDVTSYHPKSDKGILMFNKEDVYSPDENVS
GRTNRPGKEVVDPRTGRIIKVKRETPDDYLNVLKPIKGPKRMEFNPYLPKTLTPKGYAKFKLMMNVASKQ
YETLVKRLKTERTLWEDPDFPANDKAIGNLPDFRERIEWKRPHEINPNAKFFAGGASRFDIEQGALGDCW
LLAVVASISGYPQLFDQVVPKDQELKGPEYVGVVRFRFWRFGHWVEVLIDDRLPVRQGRNTLVFMHSNDP
TEFWSALLEKAYAKLNGCYAHLSGGSQSEAMEDLTGGICLSLELNQKERPSDLIDQLKIYAQRCCLMGCS
IDSSVMEQKMDNGLIGSHAYSLTGVYPVNYRGRTQWLMRLRNPWGDSHEWKGAWCDGSPQWREISEQEKK
NINLSFTADGEFWMSYEDFVTCFSRVEVCHLGLESLEYNQNFHGKRRLDEAIFSGQWQRNVNAGGCINNR
TTYWTNPQFRITVEDPDPDDDDNKCSVLIGLMQTDIRKKVGADFQPIGFMVYNAPDDLNTLLSRAQLLTR
SPIAKSQFINTREVTAQFRVPPGSYVVIPSTFDPNIEVNFILRVFSQTSITEQELDEDNTNQGLPDDVIE
ALKLEDTLLDEDQEIEQKFLAIRDPKTNAINAVKLGELLNNSTLQDIPNFQGFNKELCRSMVASVDNNLT
GHVELNEFMDLWIQAKGWKHIFIKHDVDQSGYFSAYEFREALNDAGYHVSNRLINAIINRYQDPGTDKIS
FEDFMLCMVRLKTAFETIEAHPKNIEGTSLFSAEDYLRFSVYI
|
| Epitope Information |
| IEDB Linear Epitope |
|
| IEDB ID |
Epitope |
MHC restriction |
Starting position |
Ending position |
| IEDB ID |
Epitope |
Starting position |
Ending position |
|
|
|
MRRKKQNSDSETECNGVPLNYLDILKPTLTEKRVQFNLNIPCSITPKGYAKLHEKLTSPCIPHSKGKADSMADRVYRQIFLYCTNSLNGFTHSSKSETTYASPTAMRKIKISQYEIISAKMVEAKELYQDPEFPANDASIGNLPHVSGRVEWKRPKDINPLAAFCTKSYSRFDVDQGALGDCWFASVMATVTKYPSLMSNIIPPNQTFKGSGYTGAFVFNFWRFGEWVEVVVDDRIPVVKGTCNPVFIHSTDNSEFWSCLLEKAYAKLCGSYAHLTGGFQSEAMEDFTGGICTTLILNKKERPPNLLKMMEHYTKTCCVMGADVGGDKNKRREELGLIGSHAYSVTGVGKVNYMGKDVYLVRCRNPWGERHEWKGPWSDNSPEWKDVKSKDKRALQYKPKEDGEFCSFQLTFILFISTSISRRNVLFGLPLFRFPSPFQVRACLVMQFGDFLNVCPIHFQQSFCTNPQYLFTIGTDNSGKVGKAHIIVGVMQEHRRFLYGGEYLAIGFSIFEVSELQNTRLTPEELLCRKPLLTSDYIPRREVTLEADLFPGTFILIPSTYNSNQEARYICRVFSTVKMKQLELDEENSYEGFPKKELASLELNFKQLCNPVTEKINSRILGTILDQSNFGEYMDGFTEFPSNLCSSLISSASTNLTGQIDLEEYLYLLIDLKGWMLTFNKYDDRKGCVSWFKFRDLLKSSGYKVSNRVFSVLAHRHIDHKRGHISLESYLHCMANLKFAFDVTSYHPKSDKGILMFNKEDVYSPDENVSGRTNRPGKEVVDPRTGRIIKVKRETPDDYLNVLKPIKGPKRMEFNPYLPKTLTPKGYAKFKLMMNVASKQYETLVKRLKTERTLWEDPDFPANDKAIGNLPDFRERIEWKRPHEINPNAKFFAGGASRFDIEQGALGDCWLLAVVASISGYPQLFDQVVPKDQELKGPEYVGVVRFRFWRFGHWVEVLIDDRLPVRQGRNTLVFMHSNDPTEFWSALLEKAYAKLNGCYAHLSGGSQSEAMEDLTGGICLSLELNQKERPSDLIDQLKIYAQRCCLMGCSIDSSVMEQKMDNGLIGSHAYSLTGVYPVNYRGRTQWLMRLRNPWGDSHEWKGAWCDGSPQWREISEQEKKNINLSFTADGEFWMSYEDFVTCFSRVEVCHLGLESLEYNQNFHGKRRLDEAIFSGQWQRNVNAGGCINNRTTYWTNPQFRITVEDPDPDDDDNKCSVLIGLMQTDIRKKVGADFQPIGFMVYNAPDDLNTLLSRAQLLTRSPIAKSQFINTREVTAQFRVPPGSYVVIPSTFDPNIEVNFILRVFSQTSITEQELDEDNTNQGLPDDVIEALKLEDTLLDEDQEIEQKFLAIRDPKTNAINAVKLGELLNNSTLQDIPNFQGFNKELCRSMVASVDNNLTGHVELNEFMDLWIQAKGWKHIFIKHDVDQSGYFSAYEFREALNDAGYHVSNRLINAIINRYQDPGTDKISFEDFMLCMVRLKTAFETIEAHPKNIEGTSLFSAEDYLRFSVYI
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