VIOLIN: Vaccine Investigation and Online Information Network

CSP from P. knowlesi

General Information

Protegen ID

1743

Sequence Strain (Species/Organism)

Plasmodium knowlesi strain H

Taxonomy ID

5851

Other Database IDs

CDD:319368
EnsemblGenomes-Gn:PKH_134120
EnsemblGenomes-Tr:PKH_134120
GOA:B3LAV3
InterPro: IPR001841
InterPro: IPR013083
UniProtKB/TrEMBL: B3LAV3

Molecule Role

Protective antigen

Related Vaccines(s)

P. knowlesi DNA vaccine encoding PkCSP, PkSSP2, PkAMA1, and PkMSP1p42

References

Gene Information

Gene Name

CSP from P. knowlesi

NCBI Gene ID

7322927

Protein Information

Protein Name

circumsporozoite protein, putative

NCBI Protein GI

221060580

Protein pI

5.61

Protein Weight

73901.662

Protein Length

795

Protein Note

RING finger, H2 subclass, found in the PA-TM-RING ubiquitin ligase family; cd16454

Protein Sequence

>XP_002260935.1 circumsporozoite protein, putative [Plasmodium knowlesi strain H]
MSISEHTGNEVSIAERKKKEEGSGGVINDKNVSPTDDGESMPHPMEKMKGAANDEKSVEVENCAPVGENE
LRSSVLCVGCSGEASHIEEGSAKFVGEENPRTEVDSDKKAQPEGILNEVKNVKNEIDVEKKHKTQISNND
TYVENAPNDNTCGEGCSNPHMNHDNKACDNGDDNDKIPNTGGTSNGGVIPNISGVLNVEDDCPLDEGNFS
ADDRPEENADSTSSFMLEEDINLSRRAYRNFHICSIFIHGTLLLMVTLLMGILCHDFIKLSPISQKEKTM
TYFCGLLLSMLALHLCLNLYMSLVLLRQSEVSKMLKSVEAKIHVIVLVYFSMCAYIYFFEDKYYPISSTF
SFAIILAIIYYFMPIFLYIILRLLFIVVILVLVFVKRKSPTPKKILKKLKIMKYVEYRKYCEEEACFGSA
YFTNWKELNGEGVSAPREATTTTAMEGGHIIATSGGDNKGEEVSSGDSTSNRNAEGKTISTATSCIRDIS
ANGSGHPKGGDPPSSSPNDRPTRSGNSSTRSNLERHLFYDRAGVAIGRGGGSDNRGGTRPNDRGRDDPAN
GNHQNGSDNANKHPPASYDNNCDAPNTSGEENGERNGGPNKDGKSAAVFEYFQKVLKKKNNSVQNDNVKV
VHENNMEEHSFHINIECSDYVCSICCVEYLNEDDICILPCNYLHYYHKECIFKWLKRNNDCPLCRKPIGK
I

Epitope Information

IEDB Linear Epitope