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GNA2001

General Information
Protegen ID 265
Sequence Strain (Species/Organism) Neisseria meningitidis MC58
VO ID VO_0010947
Taxonomy ID 122586
Molecule Role Protective antigen
Molecule Role Annotation Protective antigen (Pizza et al., 2000)
COG COG0791M, under M: Cell wall/membrane/envelope biogenesis
References
Pizza et al., 2000: Pizza M, Scarlato V, Masignani V, Giuliani MM, Aricò B, Comanducci M, Jennings GT, Baldi L, Bartolini E, Capecchi B, Galeotti CL, Luzzi E, Manetti R, Marchetti E, Mora M, Nuti S, Ratti G, Santini L, Savino S, Scarselli M, Storni E, Zuo P, Broeker M, Hundt E, Knapp B, Blair E, Mason T, Tettelin H, Hood DW, Jeffries AC, Saunders NJ, Granoff DM, Venter JC, Moxon ER, Grandi G, Rappuoli R. Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. Science (New York, N.Y.). 2000; 287(5459); 1816-1820. [PubMed: 10710308].
Gene Information
Gene Name GNA2001
NCBI Gene ID 904124
Genbank Accession AE002098
Locus Tag NMB2001
Gene Starting Position 2114380
Gene Ending Position 2115135
DNA Sequence 
>NC_003112.2:2114380-2115135 Neisseria meningitidis MC58 chromosome, complete genome
TATGGATTCTTTTTTCAAACCGGCAGTTTGGGCGGTTTTGTGGCTGATGTTTGCCGTCCGCCCCGCCCTT
GCCGACGAGTTGACCAACCTGCTCAGCAGCCGCGAGCAGATTCTCAGACAGTTTGCCGAAGACGAACAGC
CCGTTTTACCCATCAACCGAGCCCCCGCCCGGCGGGCGGGCAATGCCGACGAACTCATCGGCAGCGCGAT
GGGGCTTAACGAACAGCCCGTTTTACCCGTCAACCGAGTCCCCGCCCGGCGGGCGGGCAATGCCGACGAA
CTCATCGGCAACGCGATGGGGCTTAACGAACAGCCCGTTTTACCCGTCAACCGAGCCCCCGCCCGGCGGG
CGGGCAATGCCGACGAACTCATCGGCAACGCGATGGGACTTTTGGGTATTGCCTACCGCTACGGCGGCAC
ATCGGTTTCTACCGGTTTTGACTGCAGCGGCTTCATGCAGCACATCTTCAAACGCGCCATGGGCATCAAC
CTGCCGCGCACGTCGGCAGAACAGGCACGGATGGGTACGCCGGTTGCCCGAAGCGAATTGCAGCCCGGAG
ATATGGTGTTTTTCCGCACGCTCGGCGGCAGCCGCATTTCCCATGTCGGACTTTATATCGGCAACAACCG
CTTCATCCACGCGCCGCGCACGGGGAAAAATATCGAAATCACCAGCCTGAGCCACAAATATTGGAGCGGC
AAATACGCGTTCGCCCGCCGGGTCAAGAAAAACGACCCGTCCCGCTTTCTGAACTG
Protein Information
Protein Name hypothetical protein
NCBI Protein GI 15677829
Protein Accession NP_274993
Protein pI 10.78
Protein Weight 26229.95
Protein Length 251
Protein Note identified by similarity to EGAD:91561; match to protein family HMM PF00877
Protein Sequence 
>NP_274993.1 hypothetical protein NMB2001 [Neisseria meningitidis MC58]
MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAEDEQPVLPINRAPARRAGNADELIGSAM
GLNEQPVLPVNRVPARRAGNADELIGNAMGLNEQPVLPVNRAPARRAGNADELIGNAMGLLGIAYRYGGT
SVSTGFDCSGFMQHIFKRAMGINLPRTSAEQARMGTPVARSELQPGDMVFFRTLGGSRISHVGLYIGNNR
FIHAPRTGKNIEITSLSHKYWSGKYAFARRVKKNDPSRFLN
Vaxign Prediction
Localization(Probability) Unknown
(Prob.=0.25)
Adhesin Probability 0.137
Trans-membrane Helices 0
Detailed Vaxign Results Vaxign Results
Epitope Information
IEDB Linear Epitope