VIOLIN: Vaccine Investigation and Online Information Network

faeG

General Information

Protegen ID

289

Sequence Strain (Species/Organism)

Escherichia coli SE11

VO ID

VO_0010993

Taxonomy ID

562

Other Database IDs

CDD:308182

Molecule Role

Protective antigen

Molecule Role Annotation

Oral immunization of FaeG-expressing L. lactis exhibits a protective response against ETEC infection in mice (Hu et al., 2009).

References

Hu et al., 2009: Hu CX, Xu ZR, Li WF, Niu D, Lu P, Fu LL. Secretory expression of K88 (F4) fimbrial adhesin FaeG by recombinant Lactococcus lactis for oral vaccination and its protective immune response in mice. Biotechnology letters. 2009; 31(7); 991-997. [PubMed: 19277476].

Gene Information

Gene Name

faeG

NCBI Gene ID

7003192

Genbank Accession

AP009243

Locus Tag

ECSE_P3-0034

Plasmid No

pSE11-3

Gene Starting Position

32214

Gene Ending Position

33053

DNA Sequence

>NC_011416.1:32214-33053 Escherichia coli SE11 plasmid pSE11-3 DNA, complete sequence
TATGAAAAAGACTCTGATTGCACTGGCGCTGGCTGCCTCTGCTGTATCTGGTATGGCGCATGCCTGGACG
TCTGGTGACTTCAATGGCACGGTCGATATCGGTGGTAGCATTGATGCAACTAATTATCGCCAGAAATGGG
AATGGGAAGTTGGTACGGGGCTTAATGGATTTTATAATGCTCTGAGTGAGTTGACAAATAATGATACAAA
ACTGACTATTACTGTTACTGGTAATAAGCCAATTTTGTTAGGCCGAACCAAAGAAGCATTTGTAACGCCG
ACAGCAGGTGGCTGGGGTGGCATCCCTCAGATTGCATTTACCGACTATAAAGGAGCACCGGTAGAGCTCA
AAAACCCTGATGGTGAAACTAATAAAGGTTTAGCATATTTTGTTCTGCCGATGAAAAATGCAGATGGTAC
TGAAGCGGGTTCCGTGAGAGTGAATGCATCTTATGCTGGGGCTGTGGTTGAAAAGACTTCTGATAGTTCG
GCTAAATTGTTCTCTGCTTATGCCGGTGAGGTAATTCGCATCTTCAATGGCGGTCTTCCGGTGAATGTTA
CCCAGTCTGAACTGCAGTCAGGTGTTGCTGCTGCTGATAGAACAGCATTGTTTGGTAGTCTGGGGAAAGC
TGATTTGGTAGCGCAGTTTCAAGCTGTTATTCCTGGGGCTACTGTGACTGATGGGACGAGCTCAGAACAT
TGTACAATGAGACTATTGGCCTCAGCTGCCTATGCACTGGGTATTGCAGATGGTCAGACTATTGAGGCAA
CTTTTAATCAGGCTGTAACTACCAGCACTCAGTGGAGCGCTCCGCTGAACGTAGCAATTACTTATTACTA

Protein Information

Protein Name

F4 fimbrial adhesin subunit FaeG

NCBI Protein GI

WP_000751752

Protein Accession

YP_002295988

Protein pI

4.87

Protein Weight

27947.04

Protein Length

356

Protein Note

Fimbrial, major and minor subunit; pfam02432

Protein Sequence

>WP_000751752.1 F4 fimbrial adhesin subunit FaeG [Escherichia coli]
MKKTLIALAIAASAASGMAHAWMTGDFNGSVDIGGTITADDYRQKWEWEVGTGLNGFGNVLNDLTNGGTK
LTITVTGNKPILLGRTKEAFATPVIGGVDGIPQIAFTDYEGASVELRKPDGGTNKGLAYFVLPMKNAGGT
KVGSVKVNASYAGVLGRGGVTSADGELLSLFADGLSSIFYGGLPRGSELSAGSAAAARTKLFGSLSRDDI
LGQIQRVNANITSLVDVAGSYRENMEYTDGTVVSAAYALGIANGQTIEATFNQAVTTSTQWSAPLNVAIT
YY

Epitope Information

IEDB Linear Epitope