VIOLIN Logo
VO Banner
Search: for Help
Protegen Home
Introduction
Statistics
News and Updates
Protegen Query
Protegen BLAST
Selected Bacteria
Brucella spp. (26)
B. anthracis (14)
E. coli (40)
M. tuberculosis (28)
N. meningitidis (18)
Selected Viruses
Ebola virus (19)
HIV (41)
Influenza virus (50)
Selected Parasites
Plasmodium (47)
Data Submission
Data Exchange
Data Download
Documentation
FAQs
Disclaimer
Contact Us
UMMS Logo


SILV

General Information
Protegen ID 299
Sequence Strain (Species/Organism) Homo sapiens
Taxonomy ID 9606
Molecule Role Protective antigen
Molecule Role Annotation Because of the suspected homology between the human MART1 and gp100 (SILV) genes and their murine counterparts, C57BL/6 mice were immunized with these recombinant adenoviruses and demonstrated that immunization with Ad2CMV-gp100 could protect mice from murine melanoma B16 challenge administered intradermally. The anti-gp100 T cells induced by Ad2CMV-gp100 vaccinated appeared to be responsible for the protection (Zhai et al., 1996).
References
Zhai et al., 1996: Zhai Y, Yang JC, Kawakami Y, Spiess P, Wadsworth SC, Cardoza LM, Couture LA, Smith AE, Rosenberg SA. Antigen-specific tumor vaccines. Development and characterization of recombinant adenoviruses encoding MART1 or gp100 for cancer therapy. Journal of immunology (Baltimore, Md. : 1950). 1996; 156(2); 700-710. [PubMed: 8543823].
Gene Information
Gene Name SILV
NCBI Gene ID 6490
Genbank Accession AC025162
Chromosome No 12
Gene Starting Position 55954104
Gene Ending Position 55966711
DNA Sequence 
>NC_000012.12:55954104-55966711 Homo sapiens chromosome 12, GRCh38.p12 Primary Assembly
ATCAGGCTCTGAGTATTTATTTCAGTTAATAGTAGTCTCCCAGGGAAGACTGGGGGAAATATAGGTGTTT
CTGTCAACTCCAGGAAAATCACAGCATCATATGAGAGTACTCAGACCTGCTGCCCACTGAGGAGGGGGCT
GTTCTCACCAATGGGACAAGAGCAGAAGATGCGGGGTAGACGCAGCCAGTGACTGCTGCTATGTGGCAAC
TGGGGTACGGAGAAGTCTTGCTTCATAAGTCTGCGCCTGATATTGGGAGAAGGGGTAAACTGGTTAGCAA
TGGACAAAGGTAGCTTGTCTGTGCTTCTCCAAAGAAGGGAACACACCCATATCCCAGTCTGCTTAGCCTT
GATCCTAGCTTCCTCCCCTTCTCCTCACCTCCAGGGTTTACCCTCTCTTATTTCTGTGGTAACCTCTGTC
CATTCCTCCCTCACCCCGTAAGCTTTCCTGCCTGAGGACCATGCCACCCCAGGCCTGGGGGATCTGCCCT
TCTTGCAGGTAGAAAACTCAGTTCACCCCAGGCCAGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTT
GGGAGGCCAAGGTAGGCAGATCACGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGCGAAACCCTG
TCTTTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGCAGGTGCCTGAAATCCCAGCTACTCGGGAAGC
TGAAGCAGGAGAATCGCTTGAAACTGGAAGGTGGAGGTTGCAGTGAGCTGAGATTATGCCACTATACTCC
AGCCTGGGCAAAAAGGGTGAAACTCCGTCTCAAAAAAAAAAAGAAAACTCAGTTTACCCAAACTGCCCCC
ACTCTTCATATTATTAACAACAGTCATTAATATCAATTATTGCACTCTTGCTTCAGAGCCAGGTGCTTTA
CTCATTGTTTCTAATCTTTACAACAGCCCCACAGGGCAAGTATTAGTTTACCTACTTTTCAGAGGCTTAG
ACAGGTTAAGCTACTTCCCCCAGGTCCTACAAGCAAGACTGCAACCCAAGTCTGTCTAACTTAAAAGCCT
GGGCTCTTTCCTGGACACCATGCTTCCTCAAAGGGAGAGGTGGTTTCTTCTCCCCTTGAGGAAAAGTGAG
TAGTGATAATAAGGGATAAGGGGGTCTGAGCTGTGTGATGAGGCCCTTACCTATATATCAGAGATGCAAG
GACCACAGCCATCAACACCAGCAAGATGCCCACGATCAGCGGAACCTGCCCAAGGCCTGCTTCTTGACCT
GTGAGAAGAATCCCAGGCACTGCTTCACTCAGTGTCTGCTGCTTGCCAGCTGCCCTCTATCCACTCCCTT
CCTCATCTTAGCTCTTGTCCAAGGACCTACCAGGCATGATAAGCTGGGTGCTGACCACTGCCAGGCTGTT
GGTATCAGCCAGAGACACATTGAGGCAGTATGTCCCCGAGCCACCCTTCAGTATCTGGTGCAGAACCAGC
TGGCAGGCTGGGCTGGGTAGCACAGGCTGGCACAGCCGCTGGGCAGGGGGCTGGCACCCTGGCGATGAGA
TCTCCATGCAGGCTTCCTTGGGCAGCCTGGAAGAAGTGTCAGCATATATAAGGGGATCTGGGAAGGGACA
CTAAATGCCAGAGAGCGGAGAAACAGTCAACCAAAGAGTTACCAGCACACTAGTGAGACACTCACCCGCC
TTGGCAGGACACAGTCAGCTCAAATGCATCCCCCTCACCGGACGGCACAGCCTGCAGGATCTCGGCACTT
TCAATACCCTCTGCAGAGTTGCAAGCTTATCAAATTAGGATTCCTCTACCTGGCCTCCCCAAAAGCCCAG
AGACAGAAAAGCCCCAGGGCTGCTCCACCAATCCCATCCCTGTGCTTTCAAATGAGGACTCTGGCATTTG
GGTATTCTTCCTATCTAGGTGAGTAATTCCTCCCAAGGTGTGCTTCCACTGACCAGCCCTAGGTAGCACA
CAGCTGCCTCCATCAGCCACCAAAGTAGGCAAGACTCACGGACAATGTCCAGGGTGACGGAAAAGGAACC
ATATCGATACAGAACACAATCCAGGGGGACTTGTCTCTTCACCAGCCTTAAGGTGGCTGTACCATCCAGC
AGGGGGCCCAGGGAACCTGGCAGGAGAGGATCAAGGAGGCAAGATCAAGAGACAGATGACTCATCTGGAG
GCAGAGGCCAAGCAGGCATTTTTTCAGGTTGAACCAGAGTTACTGGATTCTGGAGTCACAGGCTTGGAAT
CAGATAAGACCTGGGAAACCTTATTCTATAGATAAGGAAACTGAGGCCCAGAAGAAGAAAATGACTCCTC
CAGAGTCACAGTTAGGGGTGGCATTGGAGTTTTAAAAAATCCTCAAATGTTTATCACACCCCACACTATG
TCAGGTCCTAGGCTAGACATTCAACGTGTGTTAACTCATTTAAGCATCACTGTTTCATTCCTCCCTTTTT
GCTTTGGGATGGGAATCCAGGGTTGGGAAATGGAAGGATCAGGATCTCGGAATCTGGGAAGGATTTTCGT
GCATTTATGCTTGAACAGAAAATGAGCTATAAATATTATATAAATGATCACAGTCTGTTCCCTGGTCTCG
CCAACCGTTCTCAGCAGTAGAGAAAGCAACAAGCTCTTTCCTCATGGCCTAGGGGAAGACCTTGGTTTCC
TGAACTCCAGACCTATTCCATGTCATTAAGAGAGACTGGAGGGCTTTATAGCCAGGCCAGTGAGAACTCT
GAGGGGACCATAGTGCTAAGCAAAGGATTGGGTAACATCTGAGTCCTGGGTAAGACTTACAGAGTAGAGT
AGGGTACCCCACCTCCGTGAACCTCATTCGCACTGATACTCTTACCTGTAATACTTTCCGTAGACATGAT
TGAGCTGGCATCTGGACCTTCAGGCTCAGGGATAGGTAGCTCTCTAGCTGTGGTCTCCACCCACTCTGTA
GTTGTTACCTGTGCAGCTGTGGTTCCAGAAAGCACCACAATTGATACCTCTGCAGGTGTCATACCTGTAG
CCTCTGGAGTTGACATCTCTGCCAGTGTGGTACCCATGACCTCTGAAACTGGCACCTTCTCAGGTGTCAT
ACCTGTGCTCTCTGCAGTTGGCATCTGCACAGGTGCAGTGCTTATGACTTCAGTGGTTGGCACCTGCACA
GATGTGGTTCCAGAGGGCTCTGCAGTTGGCGCCTGACCAGGTGTAGTACCCACAACTTCTGTAGTAGGCA
CTTGGCCAGCTGTGGTGTTAGGGGCCTCTGCAGTTGGCCTGTGCCCATCTGTGGTGCCTGGAACTGGGGA
GGAGCCACAGGAGGTGAGAGGAATGGCAGCCTGCAGGACCACCTGGGCAGTGACTGGGCCAGGCTCCAGG
TAAGTATGAGTGACCACAAGTGCCCGAGAGATCAGGGTTCCACTACTGTCTCCAAAGTCCCAGGTGTAGG
AGAGGTCAGCTTCAGCCAGATAGCCACTGGGGTCATGGAGCTGGAGGGCAAAGGTCAGAGGCTGATTTCT
CAGGAAGTGCTTGTTCCCTCCATCCAAGGCCCGCAACTGGGACACGCTCACGGAGAAAGGCACCTGGTCT
GGGATTGGAGCCAGAAAAGGTGAGAACCAGGCCTGAGCCACAGCTTCTCCTTTCACAGCCACACCCTCCA
ACTCCAAGCTGACTGGCTGGCCCTTCACTGGCACTAAGCCTCACATTTCTCTGCCTAGGTCTTCCTGGCC
CTTCTACTTTAAGTTTGCACAGCATTTCACCTTTCTCCTTTCCAGTCCATCCAAGCCTCCCTGCCTTCTC
TTGCCCTACAACTGGCCTTGCCCCTTCCTAAACCCTTACCAGTAATGGTGAAGGCTGAGCTGGAATGAGC
AAGAGGCACATAGCTCCGGGATCCCCGGCGATGGTAGACAGTCACTTCCATGGTGTGTGTGCCCAGCATT
GCCCTGCCTGTCCCAATGCTCAGCCCAGACACTGGGCCCCCTAGAACTTGCCAGTATTGGCCTGAAGTTT
TTGGAATGAAAAGCAAGGAAGAAGAGATTACTGGTCAAAGGGGACTGAGGGACAGGCTTCGAAACGGCAC
TGGAGATGGGAGGTCAGGAAGTATGATTACTTCTGAGGGTGTTTGGAAGGCTGTGATATGGGGGGACAGG
GAAGGGGTCCTAATGAGGCATTCCATGGGGTAGGACTACAATTGAGGAAGAGTTGCCAGAAAGAATTATG
ATAGAGTTGAAGGGGGCTAGGTGCTAAGAAAGAGAAAAGATCTAAGAGGAAAATGAAGATTAGAGAAAAT
CACAGAAGTTAAGGTGGAAGGGGCGGCCAAAAGAAAGGTGATCAGGTAGAAAGAAGTAAACACAAGTGTG
GATGATAGGCTGAGAAGGGAGTCCCTCACCCCAGGTCTTCCAGACATAAACAAAGCTTCTCTTCTGAGAC
CAAGAGCCAGATGGGCAAGGTCCACCATCAGGGAAGATGCAGGCATCGTCAGTTTCCTGGGGATACACTG
GCTGTCCTCCCCACACCTGGCTCCCTGAAAGATAAATACAGAGTCACTCTCAAACCCTGGCATTCTTTTT
TGTATATCAAAACCCCTAAAATTGCTCCCAGGGTATCAGAGAGGGGCTCTGGGAATATTCCCTAGCTAGA
AAGTACATTCTCCATGATATAACCATTTGGGGTGGTAGTTGGGGGTTGAGGGTGTGGAAACTACATTTTT
TTTTTAGAGACAGGGTCTTAGTCTGATGCCCAGGCTGGAGTGCAGTGGTGTGATCACAGCTCACTGGAGT
GTCAACCTCCCAGGGTCAAGCAATCCTCCCACCTCAGCCTCCCGAGTAGCTGGGACTACAGGTATGCACC
ACCATACCCAGCTAATTTTATTTTTTTGTAGAGACAGGGTCTTGCTATATTGCCAGGACTGGTCTTGAAC
TCCTGGGCTTAAGCAATCCTCCCACCTCAGCCTCCCGAAGTGCTGGGTTTACAGGCGTGCACCACCATGC
CTGGCCAGAAGCTATAATTTAATTGGCCAGGTGTGGTGGCTCATGGCTGTAAACCCAGCACTTTGGGAAG
CTGAGGTGGGAGGACTGCTTGAGGCATGGAATTCAAGACCAGCCTGATCAACATAGCAAGACCCTGTCTC
TACAAAATACATTTAAAAAAAATTAGCCAGGTGTGGTGGTATGCACCTGTAGTTCCAGCTACTCCAGGGG
CTGAGGAAGGAGGATCACTTGAGCCCAGGAGGTTGAGGCTGCAATTAGCTATGATCACACCACTGTACTC
CAGCCTGGGAGAGAGAGAAGGACCCCGACTTTAAAATAAATAAATAAATAAATAAATAAAATAAGAAAAA
TAAAAGAAAAAGAAGATATATGTATATATATATAGCCACATATCAAAATATTTAGAGTGATTTGCTCTAG
CTAGTGGAATAAAAATAACAGCACTAGGGGGCCAGGCGCAGTGGCTCACACCTGTAATCCTAGCACTTTG
GGAGTCTGAAGCGGTTAAATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTAAAACCCT
GTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGCTGGCGGAAGCCTATAATCCCAGCTACCCAGGAGG
CTGAGGCAGGAGAATCGCTGGAACCTGGGAGGTGGAGGCTGCAGTGAGCCAAGATCGCACCACTGCACTC
CAGCCTGAGCGACACAGCGAGACTCTGTCTCAAAAATAAATACATAAATAAATAACAGCACTAGATAGCA
TTTATTTAGCCTTTACTGTAGGCTAGAGCAGACACTACATTAAGTACTTTACACATATTATCACATTCTA
ATCCTTACAACAATCCTTTTATCTTCGGAAATGGAAACACAGTGAGGTGGGCAGATCACTTGATCTCAGG
AGTTTGAGTCATCCTGGATAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAGAATTAGCCGGGCA
TGGTGACATGCGCCTGTATCAGCTACTCGGGAGGCTACTCCCAGCTACTCAGGAGGCTGAGGCGGAAGGA
TCACTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCCTGCCACTGCACTCCAGCCTGAGCGACA
CAGCCAGACTCTGTCTCAAAAAAAAAAAAAAAGAAAAGAAAAGAAAAGAAAAGAAAAAAAAAGAAATGGA
AACACAAAACAAGTAACTTGCCCAAGGTCACATATCAAGGACAAGTTTAAATATAGGTCTGTTCAACTTC
TAGGTCCCCTGAATTCTGCTGTCCTCCACTTTAGGGACTGTAATTTTCTTTTTTCTTTTTGAGACAGGGT
CTCACTCTGTCACCCAGGCTGAAGTACAGTGGCGTGATCATGCAGTCTCGACCTCCCAGGCTCATGATCC
TCCCACCTGAGACTGCTAAGTAGCAGGGACTACAACTGTAATTTTCTTTTCTTTTTGCTTTCTGTTTTTT
TTTTTTTTTTTTTTTTTGAAATGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCATGATCTCGG
TTCACTGCAAGCTCCACCTCCTGGGTTCACGCCATTCTCCTGTCTCAGCCTCCCAAGTAGCTGGGACTAC
ATGCGCCTGCCACCACGCCCGGCTAATTTTTTGTATTTTTTTTTTAGTAGAGACAGGGTTTCACCGTGTT
AGCCAGGATGGTCTGGATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCGAAGTGCTGCGATTACA
GGCGTGAGCCACCGCGCCCGGCCTTCTCTGTGTTTTTAAATTTTAACTACAATGAGTATGTATTACACAT
ATAACTTGTTTTAAAAATTAAAGGAGGAGGCCGGGTGCGATGGCTCACGCCTGTAATCCCAGAACTTTGG
GAGGCCGAGGCGGGCGGATCACAAGGTCAGGAGATGGAGACTATACTGGCTAACACGGTGAAACCCTGTC
TCTACTAAAAATACAAAAAAAATTAGCCGGTCATGGTGGCAGGCGCCTGTAGTCCCAGCTACTCGGGAGG
CTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCAGAGCTTGCAGTGAGCCGAGATTGCGCCACTGCACTC
CAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAGAAAAAAAAAAAAAAGTAGAGAAGGAAGGGGCA
TTCCCTGAGCTCACTGGGCATACCAGGGAACCTGAGCCCTAGGAATAAGGACCTAGAATAGAGAAGTACT
CACCATTGATGATGGTATTGTTGACCCAGATAACCTGCCCATCTGGCAATACCTTTTGGCTTCCAGGGAA
GTTCAAGGCAATAGAGAAGGAGGCATTTGCACCAATCAGTGTAGGCCCATCATTACTGACCTTGAGGGAC
ACTTGACCACCTGGGAAGGAAAGCTACATTAGCTGGGACTCCTGGGCTTCCCCTCCCTGTATACGTTTCC
CCTCCTTTTCTTCCCAAGCTACACTCGATGCAGTTCAGCTTGCTTTTTTCCTCATCCCACTCCCACCATG
CCCTCCCCTGGAACTTCCAAGTTCCTACCTCTCCAGCAGTCAAGTCTCTGGGCTTCTGTCCACTCTGGAT
ACAGCTGCCTGTTCCAGGCTTTGGTTCTGAGTTGCCTTGAGACACCAAGCCAGTCCTGGTTTCTGGGTAC
TAAAAGGAATGTGCCATGAAGGGCCCTAGGATCCTTTCAGTTCCTTCTCAGGGATAACACTCTATTCATG
TCACTCCATTCATTCTCACATTCGAAGTGCATTTTTTTTTTTTTTTTTTTGAGATGGAGTTTCGCTCTTG
TTGCCCAGGCTGGAGTGCAATGGCATGATCTCGGCTCATTGCAACCTCTGTCTCCTGGGTTCAAGCGATT
CTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGTGCCACCATGCCAGGCTAATTTTGTATTT
TTAGTAGAGATGGGGTTTCTCCATGTTGGTTGGTCTGGTCTCGAACTCCCGACCTTAGGTGATCTGCCTG
CTTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCTGAAGTGCATTTTTAAAAC
TCATTTATTTGGCCGGGTGTGGTGGCTCACACCTGTAATCCCAGTACTTTGGGAGGCTGAGGCGGGTGGA
TCATGAGGTCAAGAGATAGAGACCATCCTGGCCAACATGGGGAAACCCTGTCTCTACTAAAAATACAAAA
TTAGCCGGGCATGGTGGTGCGCACCTGTAGTTCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGA
ACCCGGGAGGCAGAGGTTGCAGTGAGCTGAGATTCTGAGATTGCACCAGTGTACTCCAGCTGGCGATAGA
GTAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAACACAAAAAACCCCTTATTTATTTGTTTATTTA
TTTATTATTACTCTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGCCCCCTAGGCTGG
AATGCAGTGGCGTGATCTTGGCTCACTATAGCCTCCGCTTCCTGGATTCAAGCAATTCTCGTTCCTCAGC
CTCCCAAGTAGCTGGGACTACAGGCACCCACCACCACACCCAACTAATTTTTGTATTTTTAGTTTCGCCA
TGTTTCATGGTTTCTCCATGTTGGCCAGGTTTGTCTCAAACTCCTGACCTCAAGTGATCCAACCGCTTCG
GCCTCCCAAAGTGCTGGGATTATAGGCGTGAGCCACTGCGCCTCGCCTGTTTTGTTTTAAATCAAGACAT
AATTCACATACCATAAAATTTACTTTTAGCCAGGCATGGTGGCTCACATCTGTAATCCCAGCACTTTGAG
AGGCCGAGGCAGGTGGATCACAAGGTCAGGAGTTCGAGACCAGCCTGGCCAAGTGAAACCCTGTCTCTAC
TAAAAATACAAAAATTAGCCGGGCGTGGTAGTGGGCACCTGTAGTTCCAGCTACTCAGGGGGCTGAGGCA
GGAGAATTGCTTGAACCCAGGAGGCGGAGGTGGCAGTGAGCCGAGATCACACCACTGCACTCCAGCCTGG
GCTACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAATTTACTTTTGAACATGATCAAATTTGTGTTTT
AGAAAGATCACGATGGCAAGCAGTGAGGAGGATGGATTAGAGGCTGGCAGAGATTGGGGATGGGGACAGG
GAAGACAAAATTATTGTAACTGACCAAGAGAGGTCTGAGAAGAAAAGGATATGCTGGACCTCCATCTGCC
CCACCCAGGTCCAACAACTATCAACACCTTGCCACATTTGCTTTGTTTATCCTTACTAGTTGTTGTTTTT
GTTTTTGTTTTGGCTAAAGTATGTAAAAGCAAATCCCAGACATCGTGTTATTTTAACCCTACAAATTTAA
AATGTATGAGTATTTTCTTGCATAAGCACAATGTCATTTCATGCTAGACAAAATTATCAAACTCAGTCCA
TATAAAATTTCATGAATATCTGGAAAAATGTCTTATGATTTTTAAAATCAGGATCCAAAATATAAGTACA
GTCTTTTTGTTAAGAGCCTTAGGTGGGTGGGTGTGAACAGACTCTTTCCAGGATACATTAAGGAATATAG
TAAAAGAAAAAGACTTGAAACTGCAGCACAGCGAGGAAAGTCACATCAAGGAGAACTTCCTAGAAATCTG
TGACACTAAACATCTAGGGAGAAAGCAGGGCTGGGATATAATGTATGTATTTCAGCACAGCAGAAACTAC
CCTCACCCCATTTTTCCCTTTCCTGCAGAAACCTCTCTCCCCTCCCCTTCCCTCCCCTCTCCTCTCCTTT
CTGTATATAGTTCAGCACAGCAAAAACTACCCTCACCCCATTTTTCCCTTTCCTGCAGAAACTTCCTTCC
CTTTCCTTTCCCTTTCCCCTTTCCTTTCCTTTTGATACAGGGTTTTGCTCTCTCACCCTGCGTGCAGTGG
CACGTTCATCACTCACTGCAGCCTCAAACTCCTAGGCTGAAGCCATCTTCCTCATTAGCCTCCCAAGTGG
CTAGGACCACAGGTGCTCACCACCAAGCCTGGCTAATTTTTTTTTTTTTTTTTTTTGAGACAGAGTTTCG
CTCTTGTTGCCCAGGCTGGAAGGCTGGAGTACAATGGCACGATCTCAGCTTACTACAACCTCCGCCTCCC
GGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTGGCTGGGATTACAGGCATGCACCACCACGCCCAG
CTAATTTTGTATTTTTAGTAGAGACTGGGTTTCTCTATGTTGGTCAGGCTGGTCTCAAACTCCCAACTTC
AGCTGATCCACCTGCCTTGGTCTCGCAAAGTGCTGGGATTACAGGCGTGAGCCACCAAGCCTGGCCTAGG
CCTGGCTAATTTTTTTACGTTTCGTAGAGACAAGGTCTCACTATGTTGCTCAGGCTGGTCTTGAACTCCT
GGGCTCAAGCAATCCTATGACCACGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTACACCCGG
CCTCCTTATCTCTTTTCTTTTCTTTTCTTTTTTTATTTTTTTGAGACAGAGTCTTGCTGTTGCCCAGGCT
GGAATGCAATGGTGTGATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTCATGCCTCG
GCCTCCCAAGTAGTTGGGATTACAGGTGCGTACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGA
TGGAGTTTCACCATATTGGCCAGGCTGGTCTGACCTCAAGTGATCCACCCGTCTCAGCCTCTCAAAGTGC
TAGGATTACAGGCATGAGTTACTGTGCCGGGCCTCATCCCCTTTCTTTTTTTTTTTTTTTTTGAGACGGA
GACTCGCTCTGTCACCCAGGCTGGAGTGCATTGGTGTGATCTTGGCTCACTGCAACCTCTGCCTTCTGGG
TTCAAGTGATTCTCCAGCCTCAGCCTTCTGAGTAGCTGGGACTACAGGCATGTGCCACCATGCCCAGCTA
ATTTTTGTACTTTTAGTAGAGACGGGGGTTTCACCATATTGGCCAGGCTGGTCTCGAACTCCTGACCTCG
TGATCCACCTGCTTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACGGCGCCCGGCCTCATTCC
CTTTCTAATGTGTGCTGTAACCCTAGTTGATTCTGCTGGGGGAGGATCTGGAATCATCTATTGAGCATCC
CACCACTAGAACAAGAGAAGTCATAAGATACCCCATTCTTTCTCCACTTCCAACTCTCCTCAGAGCAGCA
CGGGACATTCCAGACCCTCTCACCACCCCACCCCCGCCCCTTGCTCCTGTCACGAGGCCCAATCCCCCAG
AGCCCTTTCATGTGATGCTCAGCTGAGACCCCTCTGCCTATCTCTCCAGCCCCAGAACAAAAGGTCTGGG
CTGTGTTCACCCGTACCCATCCCAAGAGGAGAGGATTGTATCTCCTTAGTGTTCTTACCCAATACCACAT
TCTCTGACTCCCCACTTTAAATCTCCTACCCCAAGAGACGTTTCCTAAAAGAGTCTCCTGCACATTTCAC
CCCTTTGGAGCCCGTGCTCCAGCTCACTGCCAAGGAAGCCTCAGAATCAGTGCCACAGAGACCTTCTATC
CTTCTGCCCCTCCAAGCATATGAGATTATTTTCAGGCAAAATCCCAAATCTCCATGTAGGGAGGGAGCCC
AGGTGCCCACATCCTCACTAAATCAAATGAGTGGGAGACGCCTGAAATATTGCCGCTATCTCCCATTAGG
AGGACAGAAACCAGAGCAGGGGGAATTCATCCCCAAGTTCACACCTGCTCATGTCCACATATCCACACAT
ACCTTTTGTAGCCCCCACAGCCAGCAAAGCACCTATCACAGCCAAATGAAGAAGGCATCTTTTTAGCACC
AGATCCATTGTGTTCTTCCCTCCAGCAACCAAAGGCACTGGGGGGACTGGGATAGGCCCCTATATAAGAA
AAGGGTGCTCATTTGCATAGCCCTTCCTCTTCTCCCTCAGAGAAGGCCTGGGAGGGGCCGGAGGAGAGGA
AAAAGGAAAAACTGACAAAGGGATCCTGGTCCCTAGACATTGCTTTCCCATCCTGCTACTCAATGACAGT
TTCTGGTTTCACTGGGTCACTCTCATCTTGATGCACTCCCGGGCAAGAGCTAACTGAAAGGCAGCTGCGT
AACACATACCAGACACAACAGTTTATCATGGGAGAGTGAATTAAACCAGGAACTTCTCAAAAAGACAGAA
ACAGAACCCTGCATCCCAAAACAGAGACAGTGTCGGGGTATGCTATGAGGCAGAGGCAACGACTCCTCTG
AGGCCCAGGATTCCTTTGCAACGAGATTCCCGGCTTCCTGGTTTCCAAAGGAGGCTCCTGGGCCAGGTGG
AATTTAACCTTAGGTCGATACATATTTTCCCCAGGATTGGTGAAAATAGTGAGTTAGAAATCAAGAAATC
CCTACAGACTAGAGACATAGGTAGGAAACTTGGACCCAAAGCAGGTACTTGGGAAGAGTGTTCAGCCGCC
CCACCGGGGAAGAAACTTGTCTAGCCCCCAAGAACCAAACTTGCCTGGGGCGGGATCATTTGCGGGGAGG
AGCGCTGG
Protein Information
Protein Name transcript variant 3
NCBI Protein GI 318037593
Protein Accession NP_001186982
Protein pI 4.92
Protein Weight 55125.13
Protein Length 575
Protein Note Also known as SI; SIL; ME20; PMEL; gp100; PMEL17; D12S53E
Protein Sequence 
>NP_001186982.1 melanocyte protein PMEL isoform 2 precursor [Homo sapiens]
MDLVLKRCLLHLAVIGALLAVGATKGSQVWGGQPVYPQETDDACIFPDGGPCPSGSWSQKRSFVYVWKTW
GQYWQVLGGPVSGLSIGTGRAMLGTHTMEVTVYHRRGSRSYVPLAHSSSAFTITDQVPFSVSVSQLRALD
GGNKHFLRNQPLTFALQLHDPSGYLAEADLSYTWDFGDSSGTLISRALVVTHTYLEPGPVTAQVVLQAAI
PLTSCGSSPVPGTTDGHRPTAEAPNTTAGQVPTTEVVGTTPGQAPTAEPSGTTSVQVPTTEVISTAPVQM
PTAESTGMTPEKVPVSEVMGTTLAEMSTPEATGMTPAEVSIVVLSGTTAAQVTTTEWVETTARELPIPEP
EGPDASSIMSTESITGSLGPLLDGTATLRLVKRQVPLDCVLYRYGSFSVTLDIVQGIESAEILQAVPSGE
GDAFELTVSCQGGLPKEACMEISSPGCQPPAQRLCQPVLPSPACQLVLHQILKGGSGTYCLNVSLADTNS
LAVVSTQLIMPGQEAGLGQVPLIVGILLVLMAVVLASLIYRRRLMKQDFSVPQLPHSSSHWLRLPRIFCS
CPIGENSPLLSGQQV
Epitope Information
IEDB Linear Epitope