VIOLIN: Vaccine Investigation and Online Information Network

tp92

General Information

Protegen ID

3838

Sequence Strain (Species/Organism)

Treponema pallidum subsp. pallidum

Taxonomy ID

161

Other Database IDs

CDD:227116
CDD:284624
CDD:279448

Molecule Role

Protective antigen

Molecule Role Annotation

(Cameron et al., 2000)

References

Cameron et al., 2000: Cameron CE, Lukehart SA, Castro C, Molini B, Godornes C, Van Voorhis WC. Opsonic potential, protective capacity, and sequence conservation of the Treponema pallidum subspecies pallidum Tp92. The Journal of infectious diseases. 2000; 181(4); 1401-1413. [PubMed: 10762571].

Gene Information

Gene Name

tp92

Protein Information

Protein Name

Tp92

NCBI Protein GI

AAF61471

Protein pI

8.69

Protein Weight

87871.23

Protein Length

904

Protein Note

Outer membrane protein assembly factor BamA [Cell wall/membrane/envelope biogenesis]; COG4775

Protein Sequence

>AAF61471.1 Tp92 [Treponema pallidum subsp. pallidum]
MLKKASAFLIASCCVMSLAWAQANDNWYEGKPISAISFEGLEYIARGQLDTIFSQYKGQKWTYELYLEIL
QKVYDLEYFSEVSPKAVPTDPEYQYVMLQFTVKERPSVKGIKMVGNSQIRSGDLLSKILLKKGDIYNEVK
MKVDQESLRRHYLDQGYAAVKISCEAKTEAGGVVVQFTIQEGKQTVVSRIQFKGNKAFTESVLKKVLSTQ
EARFLTSGVFKENALEADKAAVHSYYAERGYIDARVEGVAKTVDKKTDASRNLVTLTYTVVEGEQYRYGG
VTIVGNQIFSTEELQAKIRLKRGAIMNMVAFEQGFQALADAYFENGYTSNYLNKEEHRDTAEKTLSFKIT
VVERERSHVEHIMIKGTKNTKDEVILREMLLKPGDVFSKSKFTDSLRNLFNLRYFSSLVPDVRPGSEQDL
VDIILNVEEQSTANVQFGVTFSGVGEAGTFPLSLFCQWEEKNFLGKGNEISVNATLGSEAQSLKLGYVER
WFLGSPLTVGFDFELTHKNLFVYRAGAKGNGLPHPYVSKEHWANSPGLAESFRLKYSRFESAIGAHTGYQ
WYPRYAVIRVNGGVDFRVVKNFYDKDNNQPFDLTVKEQLNWTSINSFWTSVSFDGRDFAYDPSSGWFLGQ
RCTFNGLVPCLEKEHSFRSDTKAEFYVTLLNYPVSAVWNLKFVLAFYTGVSVQTYYGRRKSENGKGNGVR
SGALVIDGVLVGRGWSEDAKKNTGDLLLHHWIEFRWPLAHGIVSFDFFFDAAMVYNIESQSPNGSSSASS
SSSSSSSSSSTTSSEGLYKMSYGPGLRFTLPQFPLKLAFANTFTSPGGIPKTKKNWNFVLSFTVNNL

Epitope Information

IEDB Linear Epitope