VIOLIN: Vaccine Investigation and Online Information Network

ipaD

General Information

Protegen ID

3863

Sequence Strain (Species/Organism)

Shigella flexneri

Taxonomy ID

623

Other Database IDs

CDD:297251

Molecule Role

Protective antigen

Molecule Role Annotation

(Heine et al., 2014)

References

Heine et al., 2014: Heine SJ, Diaz-McNair J, Andar AU, Drachenberg CB, van de Verg L, Walker R, Picking WL, Pasetti MF. Intradermal delivery of Shigella IpaB and IpaD type III secretion proteins: kinetics of cell recruitment and antigen uptake, mucosal and systemic immunity, and protection across serotypes. Journal of immunology (Baltimore, Md. : 1950). 2014; 192(4); 1630-1640. [PubMed: 24453241].

Gene Information

Gene Name

ipaD

Protein Information

Protein Name

IpaD

NCBI Protein GI

ACS88189

Protein pI

6.18

Protein Weight

35633.82

Protein Length

385

Protein Note

PCR_primers=fwd_name: ipaD-F1, rev_name: ipaD-R1

Protein Sequence

>ACS88189.1 IpaD (plasmid) [Shigella flexneri]
MNITTLTNSISTSSFSPNNTNGSSTETVNSDIKTTTSSHPVSSLTMLNDTLHNIRTTNQALKKDLSQKTL
TKTSLEEIALHSSQISMDVNKSAQLLDILSKKEYPINKDARELLHSAPKEAELDGYEMISHRELWDKIAK
SINNINEQYLKVYEHAVSSYTQMYQDFSAVLSSLAGWISPGGNDGNSVKLQVKSLKDELTKLKEKYKDKP
LYPANNTVSKEQANKWLTELGGTIGKVSEKNGGYVVNINMTPIDNTLKSLDNLGGNGEVVLDNAKYQAWN
AGFSAEDETMKNNLQTLVQKYSNANSIFDNLVKVLSSTISSCTDTDKLFLHF

Epitope Information

IEDB Linear Epitope