VIOLIN: Vaccine Investigation and Online Information Network

ipaC

General Information

Protegen ID

3864

Sequence Strain (Species/Organism)

Shigella dysenteriae Sd197

Taxonomy ID

300267

Other Database IDs

CDD:185271

Molecule Role

Protective antigen

Molecule Role Annotation

The recombinant IpaC protein provided a protective system against Shigella dysenteriae type I during the challenge test(Malaei et al., 2013).

References

Malaei et al., 2013: Malaei F, Hesaraki M, Saadati M, Ahdi AM, Sadraeian M, Honari H, Nazarian S. Immunogenicity of a new recombinant IpaC from Shigella dysenteriae type I in guinea pig as a vaccine candidate. Iranian journal of immunology : IJI. 2013; 10(2); 110-117. [PubMed: 23811550].

Gene Information

Gene Name

ipaC

Protein Information

Protein Name

IpaC

NCBI Protein GI

YP_406166

Protein pI

8.42

Protein Weight

38311.96

Protein Length

427

Protein Note

pathogenicity island 1 effector protein SipC; Provisional

Protein Sequence

>YP_406166.1 IpaC (plasmid) [Shigella dysenteriae Sd197]
MEIQNTKPTQILYTDISTKQTQSSSETQKSQNYQQIAAHIPLNAGKNPVLTTTLNDDQLVKLSEQVQHDS
EIIARLTDKKMKDLSEMSHTITPENTLDISSLSSNAVSLIISVAVLLSALRTAETKLGSQLSLIAFDATK
SAAENIVRQGLAALSSSITGAVTQVGITGIGAKKTHSGISEQKGALRKNLATAQSLEKELAGSKLGLNKQ
IDTNITSPQTNSSTKILGKNKLAPDNISLSTEHKTSLSSPDISLQDKIDTQRRAYELNTLSAQQKQNIGR
ATMETSAVAGNISTSGGRYASALEEEEQLISQASSKQAEEASQVSKEASQATNQLIQKLLNIIDNINQSR
SSTASQIAGNIRA

Epitope Information

IEDB Linear Epitope