dnaE
General Information
Protegen ID
3867
Sequence Strain (Species/Organism)
Rickettsia prowazekii str
Taxonomy ID
272947
Other Database IDs
CDD:235554
Molecule Role
Protective antigen
Molecule Role Annotation
(Caro-Gomez et al. , 2014 )
References
Caro-Gomez et al. , 2014: Caro-Gomez E, Gazi M, Goez Y, Valbuena G. Discovery of novel cross-protective Rickettsia prowazekii T-cell antigens using a combined reverse vaccinology and in vivo screening approach. Vaccine . 2014; 32(39); 4968-4976. [PubMed: 25010827 ].
Gene Information
Gene Name
dnaE
Protein Information
Protein Name
DNA polymerase III subunit alpha
NCBI Protein GI
NP_221128
Protein pI
7.41
Protein Weight
128179.07
Protein Length
1284
Protein Note
DNA polymerase III subunit alpha; Validated; PRK05673
Protein Sequence
>NP_221128.1 DNA polymerase III subunit alpha [Rickettsia prowazekii str. Madrid E]
MQPEFIHLRTQSSYSFLESALTIEKVVELALLHKMPALCLSDRGNLFGSLEFSLYAVKKKLQPIHGVILN
IQYDINAFAQILLIAKDETGYKNLLKLSSLTFTKNDRKICEHIGFEDLIKYQEGVIALCCYTDGIVGKCL
LARKQEQAILFARRLQAILGDRFYFEIMRHDLPEEQFIENSYIQIASELSIPIVATNKVLFSEKSMHYAH
DVLLCISEGVTKEYPDRKTVSENCYFKSPAEMRKLFSDLPNAIQNTINLRERCYFAAHPNPPMLPNFSTQ
DISETYLIRKYATEGLLARLVTKFKAENISLEHQEKLKTEYFTRLNYELDIICNMNFAGYFLIVSDFIKW
SKKQGILVGPGRGSGAGSVVAWSLLITDLDPIKFGLLFERFLNPERISMPDFDIDFCQERREEVINYVRS
KYGPNRVGQIITFGKMQAKAVIKDVARVLSLPYKLADYLTELVPFSAINPVSLEQAIREVPELANAAKGN
GLYNLEGDAELIKLVLDTSLILEGLHRHSSTHAAGIVIAGTDLVDIVPVYKDANADMLIVGYSMKYSEIA
GLIKFDFLGLQTLTVITNCKKLLKEQGIKIDFDDMTFDDKKTYQMLCKGKGVGVFQFESIGMKDALRRLK
PDSIHDLIALGALYRPGPMENIPTYIACKHKLQQPDYLHKLLEPILEETYGVVIYQEQVQRIAQVLAGYT
LGAADLLRRAMGKKIKKEMEEQEEIFVKGAIANNISPSQAKSIFSTVAKFAGYGFNKAHAAAYGVISYQT
AYLKANYPAEFLVACLNLELNNHDKINLFLQEAKDNGIKIIAPNINISEGYFSVKSSNTVITHSTKSVIS
RLNCDIKKIAKDTAVKPLYCKDESTIIFALGAIKGVTANFGKLVTDERKARGAFKSITDFIERLPPKSIN
SKLLENLIKAGCFDELHDNRLQLFLSIPKLIAYSTSYHQEQESNQFSLIKVSSLSPTILVSSDYADKNTL
AFYEFEAMGLFLSNHPLTEYQGIFSRLNILNTRDLYNKLPNGTNRVTLAGVIQKKDSRMSARGRFVTLVL
SDPENIFELTIFSEEVLKDYVHLLDVKSLVVVNCDVVKDEGGIKLTAKSFLSIEDVMNNRQFELQLYPQN
YAELEQIITLLASRTSNGYQSNAKATIYLQSKDVKHFIAKITLSETFFLQVQDFEVLNQYIR
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
IEDB ID
Epitope
MHC restriction
Starting position
Ending position
IEDB ID
Epitope
Starting position
Ending position
MQPEFIHLRTQSSYSFLESALTIEKVVELALLHKMPALCLSDRGNLFGSLEFSLYAVKKKLQPIHGVILNIQYDINAFAQILLIAKDETGYKNLLKLSSLTFTKNDRKICEHIGFEDLIKYQEGVIALCCYTDGIVGKCLLARKQEQAILFARRLQAILGDRFYFEIMRHDLPEEQFIENSYIQIASELSIPIVATNKVLFSEKSMHYAHDVLLCISEGVTKEYPDRKTVSENCYFKSPAEMRKLFSDLPNAIQNTINLRERCYFAAHPNPPMLPNFSTQDISETYLIRKYATEGLLARLVTKFKAENISLEHQEKLKTEYFTRLNYELDIICNMNFAGYFLIVSDFIKWSKKQGILVGPGRGSGAGSVVAWSLLITDLDPIKFGLLFERFLNPERISMPDFDIDFCQERREEVINYVRSKYGPNRVGQIITFGKMQAKAVIKDVARVLSLPYKLADYLTELVPFSAINPVSLEQAIREVPELANAAKGNGLYNLEGDAELIKLVLDTSLILEGLHRHSSTHAAGIVIAGTDLVDIVPVYKDANADMLIVGYSMKYSEIAGLIKFDFLGLQTLTVITNCKKLLKEQGIKIDFDDMTFDDKKTYQMLCKGKGVGVFQFESIGMKDALRRLKPDSIHDLIALGALYRPGPMENIPTYIACKHKLQQPDYLHKLLEPILEETYGVVIYQEQVQRIAQVLAGYTLGAADLLRRAMGKKIKKEMEEQEEIFVKGAIANNISPSQAKSIFSTVAKFAGYGFNKAHAAAYGVISYQTAYLKANYPAEFLVACLNLELNNHDKINLFLQEAKDNGIKIIAPNINISEGYFSVKSSNTVITHSTKSVISRLNCDIKKIAKDTAVKPLYCKDESTIIFALGAIKGVTANFGKLVTDERKARGAFKSITDFIERLPPKSINSKLLENLIKAGCFDELHDNRLQLFLSIPKLIAYSTSYHQEQESNQFSLIKVSSLSPTILVSSDYADKNTLAFYEFEAMGLFLSNHPLTEYQGIFSRLNILNTRDLYNKLPNGTNRVTLAGVIQKKDSRMSARGRFVTLVLSDPENIFELTIFSEEVLKDYVHLLDVKSLVVVNCDVVKDEGGIKLTAKSFLSIEDVMNNRQFELQLYPQNYAELEQIITLLASRTSNGYQSNAKATIYLQSKDVKHFIAKITLSETFFLQVQDFEVLNQYIR
