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transcription-repair coupling factor

General Information
Protegen ID 3868
Sequence Strain (Species/Organism) Rickettsia prowazekii str
Taxonomy ID 272947
Other Database IDs CDD:224118
CDD:215001
CDD:278688
CDD:238005
CDD:238034
CDD:198050
Molecule Role Protective antigen
Molecule Role Annotation (Caro-Gomez et al., 2014)
References
Caro-Gomez et al., 2014: Caro-Gomez E, Gazi M, Goez Y, Valbuena G. Discovery of novel cross-protective Rickettsia prowazekii T-cell antigens using a combined reverse vaccinology and in vivo screening approach. Vaccine. 2014; 32(39); 4968-4976. [PubMed: 25010827].
Gene Information
Gene Name transcription-repair coupling factor
Protein Information
Protein Name transcription-repair coupling factor
NCBI Protein GI NP_220966
Protein pI 7.76
Protein Weight 123337.86
Protein Length 1225
Protein Note Transcription-repair coupling factor (superfamily II helicase) [Replication, recombination and repair, Transcription]; COG1197
Protein Sequence 
>NP_220966.1 transcription-repair coupling factor [Rickettsia prowazekii str. Madrid E]
MIQQKFPATAKCFYVIDNFTKNLNQDFILSVSNEEEALQLYKQALFFSSNDNIYYFPSYDTIPYDHTSPN
ANIVSRRAETLTKLITNSKGKLLITHAANLLNKLPPKDFFSKYFLKLYPKIKFTMDELSMLLVENSFTRN
TSSIDVGEFAVRGEIIDIILPGPKGYRINFSWDYIESIKEFDINTQISTKYCAELVISPANEIVLNSETI
GNFKNNYLRNFGVNHTDNPLYEAVISGRKFAGYEQLLPLFYYSCSSLVDYLNNPICIFDNLSKQAILEFE
NSYNDFYLARSKANKLKVNNFYPTLSPTSLYFTASAITELLEQKNNILISYENSEQASLIGNISSISFIE
KKTIFDKLFEIIKANFHKKIIICSSVLSSFERIKSIIQNYEYTFNEINKLDEAKASVINIGIIPLNQSFY
TKEYLFITSSELLEEKTLYTNTNKKLKNILLELDNLKEGEFVVHKDHGIGQFLKLEAFKIQGKLHDFLKI
LYFGNDKLYVPVENIEVIKKYGSDNAELNKLGSVAWNKSKAKLKNRIKEISLHLIQIAAKRKLNISTPIE
LDLEAYDKFCANFPFSETEDQLTAINDIREDLTNGMLMDRLICGDVGFGKTEVAMRAVFMVAKSLNEYLP
QVAVVVPTTILCSQHFSRFIERFKGFGLNIKQLSSVISSKEANIIRLELASGKINIIIGTHALLHKNTKF
FNLKLLIIDEEQHFGVSQKEFLKSLKSSTHVLAMSATPIPRTLQMSMTGLKELSIIATPPLNRLEVRTSV
MPFDPVIIRDALLREHFRGGRSFYVAPRIKDMEDIEKQLKQIVPELSYKIAHGKMTPSKIDEVMSEFYVG
KFDILISTTIIESGIDIAEANTMIIHKADTLGLSQLYQLRGRIGRGKIRGYAYLTVASNKKITSHSLRRL
EIIQNSCSLGSGFTIASHDADLRGFGNLIGEEQSGQIKEVGTELYQEMLEEQIALLKDDPIVLEQAFIPN
INLGLSVFIPDSYVSDSALKIGLYRRIGNLSNEMEVEKFKDEMIDRFGLLPIEFNNLLDIVKIKLLCFKL
NIENLDSGDDGFVIRFYKNADMTDKILKFVSRYSNQTKIKPNNKLVFIKKLVDKNIITEVNQLLWTLLEI
Epitope Information
IEDB Linear Epitope