VIOLIN: Vaccine Investigation and Online Information Network

NEAT

General Information

Protegen ID

3897

Sequence Strain (Species/Organism)

Bacillus anthracis

Taxonomy ID

1392

Other Database IDs

CDD:309946
CDD:132993
CDD:227223
CDD:275380
CDD:275378
CDD:306825

Molecule Role

Protective antigen

Molecule Role Annotation

(Balderas et al., 2016)

References

Balderas et al., 2016: Balderas MA, Nguyen CT, Terwilliger A, Keitel WA, Iniguez A, Torres R, Palacios F, Goulding CW, Maresso AW. Progress toward the Development of a NEAT Protein Vaccine for Anthrax Disease. Infection and immunity. 2016; 84(12); 3408-3422. [PubMed: 27647868].

Gene Information

Gene Name

NEAT

Protein Information

Protein Name

NEAT domain-containing leucine-rich repeat protein

NCBI Protein GI

WP_080489610

Protein pI

5.8

Protein Weight

81601.3

Protein Length

872

Protein Note

Iron Transport-associated domain; pfam05031

Protein Sequence

>WP_080489610.1 NEAT domain-containing leucine-rich repeat protein [Bacillus anthracis]
MIGDIILKKIYMKALVVATTLAIPFAAYSTPALAAIKIEANQSVAASDRTYDTEIKIYKDQKDEPSMVSQ
YIKDPKVAIVAGKKIVTVTMQDSDYFQYLRIEDRNQPGVFHDVKVLSEDKRKNGTKVIQFEIGEFEKKHN
MQMHILIPAIGYDHKYQVQFEIKDPTVGDKETEKPDDNSNSGNTETDKPVDNQNMITDNKLRELVNKKVF
NRKDVNTPITKEELLQVKNLFLNTNEILDYSALKYMPNLKSLTVANAKIKDPSFFANLKQLNHLALRGNE
FSDVTPLVKMDHLDSLDLSNNKITNVAPLIEMKNVKSLYLSGNQIEDVTALAKMEQLDYLNLANNKITNV
APLSALKNVTYLTLAGNQIEDIKPLYSLPLTDLVLTRNKVKDLSGIEQMKQLEELWIGKNEIKDVTPLSK
MTQLKQLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIRDVRPVIELSKT
AYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKDEGGTYSNDAVKWSTPGEKVYEFGVKDPFAD
TGIFFTGSVIQNVVESKADNISKEDNTSKEDAKVEVVEFKDVPKGHWSEEAIHYLAKENIFKGYGNGQFG
FGDSITRGQVASLVQRYLKLENKVEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEM
SVVLYKVFQLKEDGNNKVNFKDVPTGHWAEGYVKALVDNNISKGDGKERFLGDDFVTREQYAQFLYNAIT
K

Vaxign Prediction

Localization(Probability)

Cellwall
(Prob.=1)

Adhesin Probability

0.360

Trans-membrane Helices

Detailed Vaxign Results

Vaxign Results

Epitope Information

IEDB Linear Epitope