VIOLIN: Vaccine Investigation and Online Information Network

flaA chimeric flagellin

General Information

Protegen ID

3925

Sequence Strain (Species/Organism)

Helicobacter pylori

Taxonomy ID

210

Other Database IDs

CDD:237146
CDD:279061
CDD:284584
CDD:279090

Molecule Role

Protective antigen

Molecule Role Annotation

Vaccination with chimeric flagellin provided mice with significant protection against H. pylori (Mori et al., 2012).

References

Mori et al., 2012: Mori J, Vranac T, Smrekar B, Cernilec M, Serbec VČ, Horvat S, Ihan A, Benčina M, Jerala R. Chimeric flagellin as the self-adjuvanting antigen for the activation of immune response against Helicobacter pylori. Vaccine. 2012; 30(40); 5856-5863. [PubMed: 22819990].

Gene Information

Gene Name

flaA chimeric flagellin

Protein Information

Protein Name

FlaA

NCBI Protein GI

AGI42755

Protein pI

6.17

Protein Weight

47725.66

Protein Length

548

Protein Note

flagellin A; Reviewed

Protein Sequence

>AGI42755.1 FlaA, partial [Helicobacter pylori]
NINAMNAHVQSALTQNALKTSLERLSSGLRINKAADDASGMTVADSLRSQASSLGQAIANTNDGMGIIQV
ADKAMDEQLKILDTVKVKATQAAQDGQTTESRKAIQSDIVRLIQGLDNIGNTTTYNGQALLSGQFTNKEF
QVGAYSNQSIKASIGSTTSDKIGQVRIATGALITASGDISLTFKQVDGVNDVTLESVKVSSSAGTGLGVL
AEVINKNSNRTGVKAYASVITTSDVAVQSGSLSNLTLNGIHLGNIADIKKNDSDGRLVAAINAVTSETGV
EAYTDQKGRLNLRSIDGRGIEIKTDSVSNGPSALTMVNGGQDLTKGSTNYGRLSLTRLDAKSINVVSASD
SQHLGFTAIGFGESQVAETTVNLRDVTGNFNANVKSASGANYNAVIASGNQSLGSGVTTLRGAMVVIDIA
ESAMKMLDKVRSDLGSVQNQMISTVNNISITQVNVKAAESQIRDVDFAEESANFNKNNILAQSGSYAMSQ
A

Epitope Information

IEDB Linear Epitope