VIOLIN: Vaccine Investigation and Online Information Network

outer membrane protein 26

General Information

Protegen ID

3929

Sequence Strain (Species/Organism)

Helicobacter pylori

Taxonomy ID

1055532

Other Database IDs

CDD:280099

Molecule Role

Protective antigen

Molecule Role Annotation

We found that oral immunization of H. pylori-infected mice with rM. smegmatis-Omp26 induced protection, i.e., significant reduction in bacterial colonization in the stomach (Lü et al., 2009).

References

Lü et al., 2009: Lü L, Cao HD, Zeng HQ, Wang PL, Wang LJ, Liu SN, Xiang TX. Recombinant Mycobacterium smegmatis mc(2)155 vaccine expressing outer membrane protein 26 kDa antigen affords therapeutic protection against Helicobacter pylori infection. Vaccine. 2009; 27(7); 972-978. [PubMed: 19111590].

Gene Information

Gene Name

outer membrane protein 26

Protein Information

Protein Name

outer membrane protein 26

NCBI Protein GI

AFX89461

Protein pI

10.25

Protein Weight

50640.192

Protein Length

548

Protein Note

clinical isolate from Inuvialuit

Protein Sequence

>AFX89461.1 outer membrane protein 26 [Helicobacter pylori Aklavik86]
MKNTNTKEIENKRMKKGQYQTLKKGLLKTALLFSLPLSVALAEDDGFYMGIGYQIGGTQQSINNKGSTLR
NNVINGFRQVGVGIAGDNGLLSVASNTMMNALLGIGKQILSDHVATTNNAQLTQFRDLLPQIEQRYQVDK
NAYTIQALQLYLNDLLNNLVNNNNGSGSGSNPIGMGYATTIRTLSAAQTQFNLLATASVGLLNALTRVNV
NSDSEFLRGLLGRMQLFNDTSSEELGKIGNNLSKSLAGIKLQDDVKAIQDRIDAYQGSLQQLKSSLNRYN
EPYLPQFGPGKSSQHGVSNGIGIQMGYKQFFGGKRNVGLRYYAFFDYGFTQLGNLNSTINANIYTYGAGT
DFLWNIFRRVFSDQSLHVGVFGGIQLAGTTWDSSLRKQIKNLFKKNPTPTNFQFLFNLGLRAHFSSTMHR
RFLSASQSIQHGMEFGVKIPVINQRYLKANGADVDYRRLYAFYINYTIGF

Epitope Information

IEDB Linear Epitope