CFA/I
General Information
Protegen ID
3970
Sequence Strain (Species/Organism)
Escherichia coli
Taxonomy ID
562
Other Database IDs
CDD:282325
Molecule Role
Protective antigen
Molecule Role Annotation
(Zeinalzadeh et al. , 2017 )
References
Zeinalzadeh et al. , 2017: Zeinalzadeh N, Salmanian AH, Goujani G, Amani J, Ahangari G, Akhavian A, Jafari M. A Chimeric protein of CFA/I, CS6 subunits and LTB/STa toxoid protects immunized mice against enterotoxigenic Escherichia coli . Microbiology and immunology . 2017; 61(7); 272-279. [PubMed: 28543534 ].
Gene Information
Gene Name
CFA/I
Protein Information
Protein Name
colonization factor antigen I
NCBI Protein GI
AAB22177
Protein pI
5.58
Protein Weight
14379.9
Protein Length
253
Protein Note
CFA/I
Protein Sequence
>AAB22177.1 colonization factor antigen I, CFA/I [Escherichia coli, H10407 (O78:H-), Peptide, 147 aa]
VEKNITVTASVDPVIDLLQADGNALPSAVKLAYSPASKTFESYRVMTQVHTNDATKKVIVKLADTPQLTD
VLNSTVQMPISVSWGGQVLSTTAKEFEAAALGYSASGVNGVSSSQELVISAAPKTAGTAPTAGNYSGVVS
LVMTLGS
Vaxign Prediction
Localization(Probability)
Extracellular (Prob.=1)
Adhesin Probability
0.836
Trans-membrane Helices
0
Detailed Vaxign Results
Vaxign Results
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
IEDB ID
Epitope
Starting position
Ending position
2169
AKEFEAAA
93
101
5931
AYSPASKTF
32
41
5932
AYSPASKTFESYRV
32
46
9802
DPVIDLLQ
12
20
15476
FEAAAL
96
102
21379
GNALPSAV
22
30
22601
GTAPT
127
132
32523
KNITVTASV
3
12
33661
KTFESYRV
38
46
38700
LPSAVK
25
31
49029
PQLTDVLN
66
74
49302
PSAVKL
26
32
63640
TFESY
39
44
68044
VDPVIDLLQADGNAL
11
26
68248
VEKNITVTASVDPVI
1
16
68249
VEKNITVTASVDPVIDLLQADGNALPSAVKLAYSPASKTFESYRVM
1
47
68925
VIDLL
14
19
69791
VLSTTAKEFEAAALG
88
103
VEKNITVTASVDPVIDLLQADGNALPSAVKLAYSPASKTFESYRVMTQVHTNDATKKVIVKLADTPQLTDVLNSTVQMPISVSWGGQVLSTTAKEFEAAALGYSASGVNGVSSSQELVISAAPKTAGTAPTAGNYSGVVSLVMTLGS