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fspA1

General Information
Protegen ID 399
Sequence Strain (Species/Organism) Campylobacter jejuni
VO ID VO_0011047
Taxonomy ID 197
Other Database IDs CDD:330552
Molecule Role Protective antigen
Molecule Role Annotation Immunogenicity and protective efficacy of three Campylobacter jejuni flagellum-secreted proteins, FlaC, FspA1, and FspA2, were compared by use of a mouse model. Immunization with FspA1 resulted in 57.8% protection without adjuvant or 63.8% protection with adjuvant against homologous challenge with 81-176 (Baqar et al., 2008).
Related Vaccines(s) C. jejuni FspA1 protein vaccine
References
Baqar et al., 2008: Baqar S, Applebee LA, Gilliland TC Jr, Lee LH, Porter CK, Guerry P. Immunogenicity and protective efficacy of recombinant Campylobacter jejuni flagellum-secreted proteins in mice. Infection and immunity. 2008; 76(7); 3170-3175. [PubMed: 18426878].
Gene Information
Gene Name fspA1
Protein Information
Protein Name FspA1
NCBI Protein GI 116292649
Protein pI 4.34
Protein Weight 15410.38
Protein Length 187
Protein Note exonuclease subunit SbcC; Provisional; cl25731
Protein Sequence 
>ABJ97640.1 FspA1 [Campylobacter jejuni]
MQINNSLNSLSQYVKVNSNEENQNSKNQEQNALAQDPAVEVNISKEAKEKSNASNQNNSQAPAQALNAQN
NTQQDSSSNSEDKLTELTQKLAEIQAKIVELTAKMSKANEDQIKSIESQIATLNAQASTIQAQIQELQSQ
QA
Epitope Information
IEDB Linear Epitope