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OmpH-like outer membrane protein

General Information
Protegen ID 4034
Sequence Strain (Species/Organism) Chlamydophila pneumoniae
Taxonomy ID 182082
Other Database IDs CDD:225381
Molecule Role Protective antigen
Molecule Role Annotation Four of the six in vitro neutralizing antigens (Pmp2, Pmp10, OmpH-like and enolase) could inhibit Cpn dissemination in a hamster model. The results show that these Cpn proteins are immunoaccessible in infectious EBs, and recommend further investigation on their value as vaccine components.(Finco et al., 2005)
References
Finco et al., 2005: Finco O, Bonci A, Agnusdei M, Scarselli M, Petracca R, Norais N, Ferrari G, Garaguso I, Donati M, Sambri V, Cevenini R, Ratti G, Grandi G. Identification of new potential vaccine candidates against Chlamydia pneumoniae by multiple screenings. Vaccine. 2005; 23(9); 1178-1188. [PubMed: 15629361].
Gene Information
Gene Name OmpH-like outer membrane protein
Protein Information
Protein Name OmpH-like outer membrane protein
NCBI Protein GI AAP98243
Protein pI 4.77
Protein Weight 19553.64
Protein Length 250
Protein Note type strain of Chlamydophila pneumoniae;
biovar: TWAR
Protein Sequence
>AAP98243.1 OmpH-like outer membrane protein [Chlamydia pneumoniae TW-183]
MKKLLFSTFLLVLGSTSAAHANLGYVNLKRCLEESDLGKKETEELEAMKQQFVKNAEKIEEELTSIYNKL
QDEDYMESLSDSASEELRKKFEDLSGEYNAYQSQYYQSINQSNVKRIQKLIQEVKIAAESVRSKEKLEAI
LNEEAVLAIAPGTDKTTEIIAILNESFKKQN

Epitope Information
IEDB Linear Epitope