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enolase

General Information
Protegen ID 4035
Sequence Strain (Species/Organism) Chlamydophila pneumoniae
Taxonomy ID 182082
Other Database IDs CDD:213580
CDD:239429
Molecule Role Protective antigen
Molecule Role Annotation Four of the six in vitro neutralizing antigens (Pmp2, Pmp10, OmpH-like and enolase) could inhibit Cpn dissemination in a hamster model. The results show that these Cpn proteins are immunoaccessible in infectious EBs, and recommend further investigation on their value as vaccine components.(Finco et al., 2005)
References
Finco et al., 2005: Finco O, Bonci A, Agnusdei M, Scarselli M, Petracca R, Norais N, Ferrari G, Garaguso I, Donati M, Sambri V, Cevenini R, Ratti G, Grandi G. Identification of new potential vaccine candidates against Chlamydia pneumoniae by multiple screenings. Vaccine. 2005; 23(9); 1178-1188. [PubMed: 15629361].
Gene Information
Gene Name enolase
Protein Information
Protein Name enolase
NCBI Protein GI AAP98758
Protein pI 4.37
Protein Weight 44335.42
Protein Length 486
Protein Note type strain of Chlamydophila pneumoniae;
biovar: TWAR
Protein Sequence
>AAP98758.1 enolase [Chlamydia pneumoniae TW-183]
MFEAVIADIQAREILDSRGYPTLHVKVTTSTGSVGEARVPSGASTGKKEALEFRDTDSPRYQGKGVLQAV
KNVKEILFPLVKGCSVYEQSLIDSLMMDSDGSPNKETLGANAILGVSLATAHAAAATLRRPLYRYLGGCF
ACSLPCPMMNLINGGMHADNGLEFQEFMIRPIGASSIKEAVNMGADVFHTLKKLLHERGLSTGVGDEGGF
APNLASNEEALELLLLAIEKAGFTPGKDISLALDCAASSFYNVKTGTYDGRHYEEQIAILSNLCDRYPID
SIEDGLAEEDYDGWALLTEVLGEKVQIVGDDLFVTNPELILEGISNGLANSVLIKPNQIGTLTETVYAIK
LAQMAGYTTIISHRSGETTDTTIADLAVAFNAGQIKTGSLSRSERVAKYNRLMEIEEELGSEAIFTDSNV
FAYEDSEE

Epitope Information
IEDB Linear Epitope