|
|
bipB |
| General Information |
| Protegen ID |
4072 |
|
Sequence Strain (Species/Organism) |
Burkholderia pseudomallei |
|
Taxonomy ID |
28450
|
|
Other Database IDs |
CDD:332605 |
|
Molecule Role |
Protective antigen |
|
Molecule Role Annotation |
(Druar et al., 2008) |
| References |
Druar et al., 2008: Druar C, Yu F, Barnes JL, Okinaka RT, Chantratita N, Beg S, Stratilo CW, Olive AJ, Soltes G, Russell ML, Limmathurotsakul D, Norton RE, Ni SX, Picking WD, Jackson PJ, Stewart DI, Tsvetnitsky V, Picking WL, Cherwonogrodzky JW, Ketheesan N, Peacock SJ, Wiersma EJ. Evaluating Burkholderia pseudomallei Bip proteins as vaccines and Bip antibodies as detection agents. FEMS immunology and medical microbiology. 2008; 52(1); 78-87. [PubMed: 17995960].
|
| Gene Information |
|
Gene Name |
bipB |
| Protein Information |
|
Protein Name |
BipB |
|
NCBI Protein GI |
ABO26356
|
|
Protein pI |
6.41 |
|
Protein Weight |
60578.26 |
|
Protein Length |
675 |
|
Protein Note |
PHLS = Public Health Laboratory Service, Colindale, United Kingdom |
|
Protein Sequence |
>ABO26356.1 BipB [Burkholderia pseudomallei]
MSSGVQGGPAAHANAYQTHPLRDAASALGTLSPQAYVDVVSAAQRNFLERMSQLASEQCDAQPAAHDARL
DDKPALRAPQERDAPPLGASDTGSRASGAAKLTELLGVLMSVISASSLDELKQRSDIWNQMSKAAQDNLS
RLSDAFQRATDEAKAAADAAEQAAAAAKQAGADAKAADAAVDAAQKRYDDAVKQGLPDDRLQSLKAALEQ
ARQQAGDAHGRADALQADATKKLDAASALATQARACEQQVDDAVNQATQQYGASASLRTPQSPRLSGAAE
LTAVLGKLQELISSGNVKELESKQKLFTEMQAKREAELQKKSDEYQAQVKKAEEMQKTMGCIGKIVGWVI
TAVSFAAAAFTGGASLALAAVGLALAVGDEISRATTGVSFMDKLMQPVMDAILKPLMEMISSLITKALVA
CGVDQQKAELAGAILGAVVTGVALVAAAFVGASAVKAVASKVIDAMAGQLTKLMDSAIGKMLVQLIEKFS
EKSGLQALGSRTATAMTRMRRAIGVEAKEDGMLLANRFEKAGTVMNVGNQVSQAAGGIVVGVERAKAMGL
LADVKEAMYDIKLLGDLLKQAVDAFAEHNRVLAQLMQQMSDAGEMQTSTGKLILRNARAV
|
| Epitope Information |
| IEDB Linear Epitope |
|
| IEDB ID |
Epitope |
MHC restriction |
Starting position |
Ending position |
| 241665 |
DEAKAAADAAEQAAAAAKQA |
HLA-DQB1*03:02 |
151 |
171 |
| 241687 |
DTGSRASGAAKLTELLGVLM |
HLA-DQB1*03:02 |
91 |
111 |
| 241740 |
GADAKAADAAVDAAQKRYDD |
HLA-DQB1*03:02 |
171 |
191 |
| 241588 |
AGAILGAVVTGVALVAAAFV |
|
431 |
451 |
| 241929 |
LTAVLGKLQELISSGNVKEL |
|
281 |
301 |
| 242183 |
VSQAAGGIVVGVERAKAMGL |
|
541 |
561 |
| 242120 |
TKLMDSAIGKMLVQLIEKFS |
|
471 |
491 |
| 242131 |
TQARACEQQVDDAVNQATQQ |
|
241 |
261 |
| 242154 |
VDAAQKRYDDAVKQGLPDDR |
|
181 |
201 |
| 242098 |
SVISASSLDELKQRSDIWNQ |
|
111 |
131 |
| 242108 |
TAVSFAAAAFTGGASLALAA |
|
351 |
371 |
| 242114 |
TGGASLALAAVGLALAVGDE |
|
361 |
381 |
| 242038 |
RLSDAFQRATDEAKAAADAA |
HLA-DQB1*03:02 |
141 |
161 |
| 242058 |
RTATAMTRMRRAIGVEAKED |
|
501 |
521 |
| 242062 |
SAAQRNFLERMSQLASEQCD |
HLA-DRB1*01:01 |
41 |
61 |
| 242017 |
QSPRLSGAAELTAVLGKLQE |
|
271 |
291 |
| 242024 |
RAIGVEAKEDGMLLANRFEK |
|
511 |
531 |
| 242023 |
RADALQADATKKLDAASALA |
|
221 |
241 |
| 241960 |
MSQLASEQCDAQPAAHDARL |
|
51 |
71 |
| 242000 |
QAKREAELQKKSDEYQAQVK |
|
311 |
331 |
| 241944 |
MDKLMQPVMDAILKPLMEMI |
|
391 |
411 |
| 241946 |
MLVQLIEKFSEKSGLQALGS |
|
481 |
501 |
| 241958 |
MSKAAQDNLSRLSDAFQRAT |
|
131 |
151 |
| 241915 |
LQSLKAALEQARQQAGDAHG |
|
201 |
221 |
| 241916 |
LRDAASALGTLSPQAYVDVV |
|
21 |
41 |
| 241926 |
LSPQAYVDVVSAAQRNFLER |
|
31 |
51 |
| 241882 |
LADVKEAMYDIKLLGDLLKQ |
|
561 |
581 |
| 241898 |
LISSGNVKELESKQKLFTEM |
|
291 |
311 |
| 241903 |
LKQRSDIWNQMSKAAQDNLS |
|
121 |
141 |
| 241837 |
KAEEMQKTMGCIGKIVGWVI |
|
331 |
351 |
| 241851 |
KKLDAASALATQARACEQQV |
|
231 |
251 |
| 241853 |
KLTELLGVLMSVISASSLDE |
|
101 |
121 |
| 241871 |
KSDEYQAQVKKAEEMQKTMG |
|
321 |
341 |
| 241817 |
IKLLGDLLKQAVDAFAEHNR |
|
571 |
591 |
| 241660 |
DAGEMQTSTGKLILRNARAV |
|
601 |
621 |
| 242093 |
SSLITKALVACGVDQQKAEL |
|
411 |
431 |
| 241879 |
KVIDAMAGQLTKLMDSAIGK |
|
461 |
481 |
| 241707 |
EKSGLQALGSRTATAMTRMR |
|
491 |
511 |
| 242169 |
VLAQLMQQMSDAGEMQTSTG |
|
591 |
611 |
| 242195 |
YGASASLRTPQSPRLSGAAE |
|
261 |
281 |
| 241596 |
AGTVMNVGNQVSQAAGGIVV |
|
531 |
551 |
| 241791 |
GVERAKAMGLLADVKEAMYD |
|
551 |
571 |
| 241828 |
ISRATTGVSFMDKLMQPVMD |
|
381 |
401 |
| 242162 |
VGLALAVGDEISRATTGVSF |
|
371 |
391 |
| 241748 |
GASAVKAVASKVIDAMAGQL |
|
451 |
471 |
| 241761 |
GMLLANRFEKAGTVMNVGNQ |
|
521 |
541 |
| 241790 |
GVALVAAAFVGASAVKAVAS |
|
441 |
461 |
| 241723 |
ESKQKLFTEMQAKREAELQK |
|
301 |
321 |
| 241717 |
EQAAAAAKQAGADAKAADAA |
|
161 |
181 |
| 241719 |
ERDAPPLGASDTGSRASGAA |
|
81 |
101 |
| 241663 |
DDAVNQATQQYGASASLRTP |
|
251 |
271 |
| 241653 |
CIGKIVGWVITAVSFAAAAF |
|
341 |
361 |
| 241652 |
CGVDQQKAELAGAILGAVVT |
|
421 |
441 |
| 241642 |
AVDAFAEHNRVLAQLMQQMS |
|
581 |
601 |
| 241644 |
AVKQGLPDDRLQSLKAALEQ |
|
191 |
211 |
| 241598 |
AILKPLMEMISSLITKALVA |
|
401 |
421 |
| 241625 |
ARQQAGDAHGRADALQADAT |
|
211 |
231 |
| IEDB ID |
Epitope |
Starting position |
Ending position |
|
|
|
MSSGVQGGPAAHANAYQTHPLRDAASALGTLSPQAYVDVVSAAQRNFLERMSQLASEQCDAQPAAHDARLDDKPALRAPQERDAPPLGASDTGSRASGAAKLTELLGVLMSVISASSLDELKQRSDIWNQMSKAAQDNLSRLSDAFQRATDEAKAAADAAEQAAAAAKQAGADAKAADAAVDAAQKRYDDAVKQGLPDDRLQSLKAALEQARQQAGDAHGRADALQADATKKLDAASALATQARACEQQVDDAVNQATQQYGASASLRTPQSPRLSGAAELTAVLGKLQELISSGNVKELESKQKLFTEMQAKREAELQKKSDEYQAQVKKAEEMQKTMGCIGKIVGWVITAVSFAAAAFTGGASLALAAVGLALAVGDEISRATTGVSFMDKLMQPVMDAILKPLMEMISSLITKALVACGVDQQKAELAGAILGAVVTGVALVAAAFVGASAVKAVASKVIDAMAGQLTKLMDSAIGKMLVQLIEKFSEKSGLQALGSRTATAMTRMRRAIGVEAKEDGMLLANRFEKAGTVMNVGNQVSQAAGGIVVGVERAKAMGLLADVKEAMYDIKLLGDLLKQAVDAFAEHNRVLAQLMQQMSDAGEMQTSTGKLILRNARAV
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