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hflX

General Information
Protegen ID 4085
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae
Taxonomy ID 715
Other Database IDs CDD:330486
Molecule Role Protective antigen
Molecule Role Annotation Six in vivo-induced (IVI) antigens-RnhB, GalU, GalT, Apl_1061, Apl_1166, and HflX used as vaccine candidates provide partial protection against Actinobacillus pleuropneumoniae infection in a mouse model, which could be used as potential vaccine candidates in piglets.(Zhang et al., 2016)
References
Zhang et al., 2016: Zhang F, Cao S, Zhu Z, Yang Y, Wen X, Chang YF, Huang X, Wu R, Wen Y, Yan Q, Huang Y, Ma X, Zhao Q. Immunoprotective Efficacy of Six <i>In vivo</i>-Induced Antigens against <i>Actinobacillus pleuropneumoniae</i> as Potential Vaccine Candidates in Murine Model. Frontiers in microbiology. 2016; 7; 1623. [PubMed: 27818646].
Gene Information
Gene Name hflX
Protein Information
Protein Name GTPase HflX
NCBI Protein GI ASU15836
Protein pI 6.07
Protein Weight 42787.812
Protein Length 470
Protein Note GTP-binding GTPase Middle Region; cl25665
Protein Sequence
>ASU15836.1 GTPase HflX [Actinobacillus pleuropneumoniae]
MEFQTLAESAGVEILATLTTSAPHIKYFVGQGKADEIAQAVKDLEATVVLVNHELSPSQTRNLQALCECR
VVDRTGLILDIFAQRARSHEGKLQVELAQLKHLATRLVRRLGNQDQQKGGAVGLRGPGETQLETDRRLIK
VRIQQLQNRLEKVNKQRSQNRKTRQKADIPTVSLVGYTNAGKSTLFNAITNAGVYAADQLFATLDPTLRR
MQIQDVGTTILADTVGFIRFLPHDLVSAFKSTLQETTEASLLLHVIDAADDRKNENIDAVNQVLDEIGAL
EVPTLLIYNKVDKLEGVMPHIERNDNGKPVAVYLSAQANQGIDLLYEAIRECLRNELVCEKVLLPATSGQ
IYTQFHLQRCIKNESFNQFGDRLVEVEVDLVQWNKWLKQFPELTEYVEFASWAED

Epitope Information
IEDB Linear Epitope