VIOLIN: Vaccine Investigation and Online Information Network

hypothetical protein APL_1061

General Information

Protegen ID

4086

Sequence Strain (Species/Organism)

Actinobacillus pleuropneumoniae

Taxonomy ID

416269

Other Database IDs

CDD:324543

Molecule Role

Protective antigen

Molecule Role Annotation

Six in vivo-induced (IVI) antigens-RnhB, GalU, GalT, Apl_1061, Apl_1166, and HflX used as vaccine candidates provide partial protection against Actinobacillus pleuropneumoniae infection in a mouse model, which could be used as potential vaccine candidates in piglets.(Zhang et al., 2016)

References

Zhang et al., 2016: Zhang F, Cao S, Zhu Z, Yang Y, Wen X, Chang YF, Huang X, Wu R, Wen Y, Yan Q, Huang Y, Ma X, Zhao Q. Immunoprotective Efficacy of Six <i>In vivo</i>-Induced Antigens against <i>Actinobacillus pleuropneumoniae</i> as Potential Vaccine Candidates in Murine Model. Frontiers in microbiology. 2016; 7; 1623. [PubMed: 27818646].

Gene Information

Gene Name

hypothetical protein APL_1061

Protein Information

Protein Name

hypothetical protein

NCBI Protein GI

ABN74153

Protein pI

9.35

Protein Weight

21642.16

Protein Length

298

Protein Note

Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; cl09930

Protein Sequence

>ABN74153.1 hypothetical protein APL_1061 [Actinobacillus pleuropneumoniae serovar 5b str. L20]
MKKFMTMTSILALSSMALTSFANAEETTAQAQNNVQTEMPATAEKAVPVIGQQAVEFTRKAADQMMQGQG
RGQNFHSFHHNGKHPYDMMRMMAYHHPHQFGGYKPQGFIDQNAVAKDAKAALEAKDRSFVQLEGSISKQV
NDTEYTFVDSTGQIKIEVPPSLWRGLSVGPQDKVRIDGILDKQWEQPEIKVKNITRLK

Epitope Information

IEDB Linear Epitope