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cpxD

General Information
Protegen ID 4096
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 2 str. S1536
Taxonomy ID 715
Other Database IDs CDD:132072
CDD:280687
Molecule Role Protective antigen
Molecule Role Annotation These data identify OM proteins(CpxD) that demonstrate immunogenicity and upregulation under conditions mimicking infection, providing emphasis on lipoproteins as an important class of antigens to exploit for vaccine development for A. pleuropneumoniae.(Chung et al., 2012)
References
Chung et al., 2012: Chung JW, Küster-Schöck E, Gibbs BF, Jacques M, Coulton JW. Immunoproteomic analyses of outer membrane antigens of Actinobacillus pleuropneumoniae grown under iron-restricted conditions. Veterinary microbiology. 2012; 159(1-2); 187-194. [PubMed: 22541161].
Gene Information
Gene Name cpxD
Protein Information
Protein Name CpxD
NCBI Protein GI AAB64442
Protein pI 7.5
Protein Weight 38942.04
Protein Length 452
Protein Note J45 is a serotype 5a strain of Actinobacillus pleuropneumoniae
Protein Sequence
>AAB64442.1 CpxD [Actinobacillus pleuropneumoniae]
MKLIKLRLLLSLGLVASLAACSSLPTSGPSHSAILEANSQNSDKPLPEVNLVELDNGLVQQLYQTQQSQQ
FSGFLGTAGGAGYAGAVNVGDVLEISIWEAPPAVLFGGTFSSEGQGSGHLTQLPAQMVNQNGTVTVPFVG
NIRVAGKTPEAIQSQIVGALQRKANQPQVLVKIANNNSADVTVIRQGNSIRMPLSANNERVLDAVAAVGG
TTENIEDVTVKLTRGSQVKTLAFETLISDPAQNIMLRAGDVVSLLNTPYSFTGLGAVGNNQQMKFSSKGI
TLAEAIGKMGGLIDTRSDPRGVFVFRHVPFSQLSLDQQTQWGAKGYGMGMDVPTVYRVNLLEPQSLFLLQ
RFPMQDKDIVYVSNAPLSEFQKFLRMIFSITSPVTSTTNAIRAY

Epitope Information
IEDB Linear Epitope