VIOLIN: Vaccine Investigation and Online Information Network

M6

General Information

Protegen ID

4106

Sequence Strain (Species/Organism)

Streptococcus pyogenes

Taxonomy ID

1314

Other Database IDs

CDD:273479
CDD:287215
CDD:279132

Molecule Role

Protective antigen

Molecule Role Annotation

(Mansour and Abdelaziz, 2016)

References

Mansour and Abdelaziz, 2016: Mansour NM, Abdelaziz SA. Oral immunization of mice with engineered Lactobacillus gasseri NM713 strain expressing Streptococcus pyogenes M6 antigen. Microbiology and immunology. 2016; 60(8); 527-532. [PubMed: 27301486].

Gene Information

Gene Name

Protein Information

Protein Name

M6 mature peptide

NCBI Protein GI

AAA26920

Protein pI

9.97

Protein Weight

51620.25

Protein Length

549

Protein Note

M6 signal peptide

Protein Sequence

>AAA26920.1 M6 precursor peptide [Streptococcus pyogenes]
MAKNNTNRHYSLRKLKKGTASVAVALSVIGAGLVVNTNEVSARVFPRGTVENPDKARELLNKYDVENSML
QANNDKLTTENNNLTDQNKNLTTENKNLTDQNKNLTTENKNLTDQNKNLTTENKELKAEENRLTTENKGL
TKKLSEAEEEAANKERENKEAIGTLKKTLDETVKDKIAKEQESKETIGTLKKTLDETVKDKIAKEQESKE
TIGTLKKTLDETVKDKIAKEQESKETIGTLKKILDETVKDKIAREQKSKQDIGALKQELAKKDEGNKVSE
ASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLRRDLDASREAKKQVEKALEEAN
SKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKLRAGKASDSQTPDAKPGNK
VVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN

Epitope Information

IEDB Linear Epitope