VIOLIN: Vaccine Investigation and Online Information Network

M18

General Information

Protegen ID

4116

Sequence Strain (Species/Organism)

Streptococcus pyogenes

Taxonomy ID

1314

Other Database IDs

CDD:291694
CDD:295219
CDD:279132

Molecule Role

Protective antigen

Molecule Role Annotation

(McNeil et al., 2005)

References

McNeil et al., 2005: McNeil SA, Halperin SA, Langley JM, Smith B, Warren A, Sharratt GP, Baxendale DM, Reddish MA, Hu MC, Stroop SD, Linden J, Fries LF, Vink PE, Dale JB. Safety and immunogenicity of 26-valent group a streptococcus vaccine in healthy adult volunteers. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2005; 41(8); 1114-1122. [PubMed: 16163629].

Gene Information

Gene Name

M18

Protein Information

Protein Name

LPXTG cell wall anchor domain-containing protein

NCBI Protein GI

WP_011018277

Protein pI

10.02

Protein Weight

44009.252

Protein Length

497

Protein Note

Ciliary rootlet component, centrosome cohesion; pfam15035

Protein Sequence

>WP_011018277.1 LPXTG cell wall anchor domain-containing protein [Streptococcus pyogenes]
MVRKDANRQYSLRKLKKSTASVAVALSALGVGLAVNQTEVSAAPLTRATADNKDELIKRANGYEIQNHQL
TVENKKLKIDKEQLTKENDDLKTEKDQLEQRSEKLATQKENLEKEVAEAKHKNETLNINNDDLTKKLNET
RQELANKQQESKENEKTLNELLEKTVKDKIAREQKSKQDFGALKQELAKKEEQNKISEASRKGLRRDLDA
SREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKE
LEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKLRAEKASDSQTPDAKPGNKAVPGKGQAPQAG
TKPNQNKAPMKETKRQLPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN

Epitope Information

IEDB Linear Epitope