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M22

General Information
Protegen ID 4117
Sequence Strain (Species/Organism) Streptococcus pyogenes
Taxonomy ID 1314
Other Database IDs CDD:224135
Molecule Role Protective antigen
Molecule Role Annotation (McNeil et al., 2005)
References
McNeil et al., 2005: McNeil SA, Halperin SA, Langley JM, Smith B, Warren A, Sharratt GP, Baxendale DM, Reddish MA, Hu MC, Stroop SD, Linden J, Fries LF, Vink PE, Dale JB. Safety and immunogenicity of 26-valent group a streptococcus vaccine in healthy adult volunteers. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2005; 41(8); 1114-1122. [PubMed: 16163629].
Gene Information
Gene Name M22
Protein Information
Protein Name peptidase M22
NCBI Protein GI AKI36048
Protein pI 5.34
Protein Weight 24486.34
Protein Length 288
Protein Note tRNA A37 threonylcarbamoyladenosine modification protein TsaB [Translation, ribosomal structure and biogenesis]; COG1214
Protein Sequence 
>AKI36048.1 peptidase M22 [Streptococcus pyogenes]
MKTLAFDTSNKTLSLAILDDETLLADMTLNIQKNHSVSLMPAIDFLMTCTDLKPQDLERIVAAKGPGSYT
GLRVAVATAKTLAYSLNIALVGISSLYALAASTCKQYPNTLVVPLIDARRQNAYVGYYRQGKSVMPQAHA
SLEVIIEQLVEEGQLIFVGETAPFAEQIQKKLPQAILLPTLPSAYECGLLGQSLAPENVDAFVPQYLKRV
EAEENWLKDNEIKDDSHYVKRI
Epitope Information
IEDB Linear Epitope