speB
General Information
Protegen ID
4122
Sequence Strain (Species/Organism)
Streptococcus pyogenes
Taxonomy ID
1314
Other Database IDs
CDD:316273
Molecule Role
Protective antigen
Molecule Role Annotation
(Tsao et al. , 2013 )
References
Tsao et al. , 2013: Tsao N, Cheng MH, Yang HC, Wang YC, Liu YL, Kuo CF. Determining antibody-binding site of streptococcal pyrogenic exotoxin B to protect mice from group a streptococcus infection. PloS one . 2013; 8(1); e55028. [PubMed: 23383045 ].
Gene Information
Gene Name
speB
Protein Information
Protein Name
strepotococcal cysteine protease (streptopain) protein SpeB
NCBI Protein GI
ANC27833
Protein pI
8.97
Protein Weight
40955.34
Protein Length
502
Protein Note
Spi protease inhibitor; pfam13734
Protein Sequence
>ANC27833.1 strepotococcal cysteine protease (streptopain) protein SpeB [Streptococcus pyogenes]
MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAITFIQKSAAIKAGARSAEDIKLDKVNLG
GELSGSNMYVYNISTGGFVIVSGDKRSPEILGYSTSGSFDVNGKENIASFMESYVEQIKENKKLDTTYAG
TAEIKQPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKG
LKDYTYTLSSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSS
GSAGSSRVQRALKENFGYNQSVHQINRGDFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGR
NFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSAVVGIKP
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
IEDB ID
Epitope
MHC restriction
Starting position
Ending position
IEDB ID
Epitope
Starting position
Ending position
594134 ALGTGGGAGGFNGYQSAVVGIKP
376
399
179964 DGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSAVVGIKP
345
399
MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAITFIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILGYSTSGSFDVNGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQSVHQINRGDFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSAVVGIKP
