speA
General Information
Protegen ID
4123
Sequence Strain (Species/Organism)
Streptococcus pyogenes
Taxonomy ID
1314
Other Database IDs
CDD:279467
Molecule Role
Protective antigen
Molecule Role Annotation
(Morefield et al. , 2014 )
References
Morefield et al. , 2014: Morefield G, Touhey G, Lu F, Dunham A, HogenEsch H. Development of a recombinant fusion protein vaccine formulation to protect against Streptococcus pyogenes . Vaccine . 2014; 32(30); 3810-3815. [PubMed: 24837509 ].
Gene Information
Gene Name
speA
Protein Information
Protein Name
streptococcal pyrogenic exotoxin SpeA
NCBI Protein GI
WP_011285560
Protein pI
5.97
Protein Weight
27919.46
Protein Length
335
Protein Note
Staphylococcal/Streptococcal toxin, OB-fold domain; pfam01123
Protein Sequence
>WP_011285560.1 streptococcal pyrogenic exotoxin SpeA [Streptococcus pyogenes]
MENNKKVLKKMVFFVLVTFLGLTISQEVFAQQDPDPSQLHRSSLVKNLQNIYFLYEGDPVTHENVKSVDQ
LLSHDLIYNVSGPNYDKLKTELKNQEMATLFKDKNVDIYSVEYYHLCYLCENAERSACIYGGVTNHEGNH
LEIPKKIVVKVSIDGIQSLSFDIETNKKMVTAQELDYKVRKYLTDNKQLYTNGPSKYETGYIKFIPKNKE
SFWFDFFPEPEFTQSKYLMIYKDNETLDSNTSQIEVYLTTK
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
IEDB ID
Epitope
MHC restriction
Starting position
Ending position
IEDB ID
Epitope
Starting position
Ending position
MENNKKVLKKMVFFVLVTFLGLTISQEVFAQQDPDPSQLHRSSLVKNLQNIYFLYEGDPVTHENVKSVDQLLSHDLIYNVSGPNYDKLKTELKNQEMATLFKDKNVDIYSVEYYHLCYLCENAERSACIYGGVTNHEGNHLEIPKKIVVKVSIDGIQSLSFDIETNKKMVTAQELDYKVRKYLTDNKQLYTNGPSKYETGYIKFIPKNKESFWFDFFPEPEFTQSKYLMIYKDNETLDSNTSQIEVYLTTK
