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spa

General Information
Protegen ID 4126
Sequence Strain (Species/Organism) Streptococcus pyogenes
Taxonomy ID 1314
Other Database IDs CDD:309682
CDD:331876
CDD:330553
CDD:307064
Molecule Role Protective antigen
Molecule Role Annotation (Niedermeyer et al., 2014)
References
Niedermeyer et al., 2014: Niedermeyer SE, Penfound TA, Hohn C, Li Y, Homayouni R, Zhao J, Dale JB. Group A streptococcus expresses a trio of surface proteins containing protective epitopes. Clinical and vaccine immunology : CVI. 2014; 21(10); 1421-1425. [PubMed: 25080552].
Gene Information
Gene Name spa
Protein Information
Protein Name streptococcal protective antigen
NCBI Protein GI ACD81471
Protein pI 6.3
Protein Weight 58450.81
Protein Length 632
Protein Note YSIRK type signal peptide; pfam04650
Protein Sequence 
>ACD81471.1 streptococcal protective antigen [Streptococcus pyogenes]
MFLRNKKQKFSIRKLSAGAASVLVAASVLGGAVVNVHAEDRINSDINRRIVDKKDAENLRNAIIAKGARL
KNDSEVISFLREALSNATVDTLATLLSGIDPARFGYSNSQLEFYSRQLGSLNSGVSDWQQGSVNLKTLLI
EEFAKRIKSEQKLKEVLAEQAAELELRKSEESELKTQKERLESKLENAEYATAIKQKELDDAKEANKTLS
ESIAKTLSRSTKEKDKLKEELVKEKTKAAKIAKELMDKLTASEKDKDRAIQITTELTNRLHETEASRDKA
FAVSTELANKLAAKTAEAEKLMQNVGSLDRLVESAKREIAEKLAEIDQLTADKAKADAELATANDTIASL
QTELEKAKTELAVSERLIESGKREMAELQKQKDASDKALAESQANVAELEKQKAASDAKVAELEKEVEAA
KAEVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEMLEKKDHANADLQAEINRLKQE
LADRIKSLSQGGRASQANPGSTTAKAGQLPSTGESANPFFTIAALTVIAGAGMAVVSPKRKEN
Epitope Information
IEDB Linear Epitope