putative secreted protein SPy0019
General Information
Protegen ID
4134
Sequence Strain (Species/Organism)
Streptococcus pyogenes
Taxonomy ID
160490
Other Database IDs
CDD:226400
Molecule Role
Protective antigen
Molecule Role Annotation
(Bensi et al. , 2012 )
References
Bensi et al. , 2012: Bensi G, Mora M, Tuscano G, Biagini M, Chiarot E, Bombaci M, Capo S, Falugi F, Manetti AG, Donato P, Swennen E, Gallotta M, Garibaldi M, Pinto V, Chiappini N, Musser JM, Janulczyk R, Mariani M, Scarselli M, Telford JL, Grifantini R, Norais N, Margarit I, Grandi G. Multi high-throughput approach for highly selective identification of vaccine candidates: the Group A Streptococcus case. Molecular & cellular proteomics : MCP . 2012; 11(6); M111.015693. [PubMed: 22286755 ].
Gene Information
Gene Name
putative secreted protein SPy0019
Protein Information
Protein Name
putative secreted protein
NCBI Protein GI
NP_268436
Protein pI
8.81
Protein Weight
39963.99
Protein Length
476
Protein Note
Uncharacterized N-terminal domain of peptidoglycan hydrolase CwlO [Function unknown]; COG3883
Protein Sequence
>NP_268436.1 putative secreted protein [Streptococcus pyogenes M1 GAS]
MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTEQKAAQNQVSALQAQVSSLQSEQDKLT
ARNTELEALSKRFEQEIKALTSQIVARNEKLKNQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRA
VSANAKLLEQQKADKVSLEEKQAANQTAINTIAANMAMAEENQNTLRTQQANLVAATANLALQLASATED
KANLVAQKEAAEKAAAEALAQEQAAKVKAQEQAAQQAASVEAAKSAITPAPQATPAAQSSNAIEPAALTA
PAAPSAGPQTSYDSSNTYPVGQCTWGAKSLAPWAGNNWGNGGQWAYSAQAAGYRTGSTPMVGAIAVWNDG
GYGHVAVVVEVQSASSIRVMESNYSGRQYIADHRGWFNPTGVTFIYPH
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
IEDB ID
Epitope
MHC restriction
Starting position
Ending position
IEDB ID
Epitope
Starting position
Ending position
519530 KANLVAQKEAAEKAA
211
226
520757 LALQLASATEDKANL
200
215
511391 ANLALQLASATEDKA
198
213
522939 NLALQLASATEDKAN
199
214
527200 TANLALQLASATEDK
197
212
514449 EEKQAANQTAINTIA
159
174
514820 EKQAANQTAINTIAA
160
175
523242 NRLVAINRAVSANAK
132
147
520990 LEEKQAANQTAINTI
158
173
519527 KALTSQIVARNEKLK
88
103
511338 ALTSQIVARNEKLKN
89
104
522215 LTSQIVARNEKLKNQ
90
105
528163 TSQIVARNEKLKNQA
91
106
510760 ADKVSLEEKQAANQT
153
168
513101 DKVSLEEKQAANQTA
154
169
520623 KVSLEEKQAANQTAI
155
170
529520 VSLEEKQAANQTAIN
156
171
526220 SLEEKQAANQTAINT
157
172
518713 IKALTSQIVARNEKL
87
102
519476 KADKVSLEEKQAANQ
152
167
514707 EIKALTSQIVARNEK
86
101
511216 AKQDSIISNLTTEQK
32
47
520252 KQDSIISNLTTEQKA
33
48
518220 IAKQDSIISNLTTEQ
31
46
519882 KIAKQDSIISNLTTE
30
45
527019 STKIAKQDSIISNLT
28
43
511794 AQKEAAEKAAAEALA
216
231
524216 QKEAAEKAAAEALAQ
217
232
519665 KEAAEKAAAEALAQE
218
233
511400 ANLVAQKEAAEKAAA
212
227
522983 NLVAQKEAAEKAAAE
213
228
522248 LVAQKEAAEKAAAEA
214
229
528424 VAQKEAAEKAAAEAL
215
230
520241 KQAANQTAINTIAAN
161
176
522145 LSTKIAKQDSIISNL
27
42
520438 KSISDVVNRLVAINR
125
140
526104 SISDVVNRLVAINRA
126
141
526178 SKSISDVVNRLVAIN
124
139
511923 ARNEKLKNQARSAYK
96
111
525081 RNEKLKNQARSAYKN
97
112
522724 NEKLKNQARSAYKNN
98
113
514811 EKLKNQARSAYKNNE
99
114
524208 QKADKVSLEEKQAAN
151
166
151111 AEKAA
221
226
MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTEQKAAQNQVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEKLKNQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRAVSANAKLLEQQKADKVSLEEKQAANQTAINTIAANMAMAEENQNTLRTQQANLVAATANLALQLASATEDKANLVAQKEAAEKAAAEALAQEQAAKVKAQEQAAQQAASVEAAKSAITPAPQATPAAQSSNAIEPAALTAPAAPSAGPQTSYDSSNTYPVGQCTWGAKSLAPWAGNNWGNGGQWAYSAQAAGYRTGSTPMVGAIAVWNDGGYGHVAVVVEVQSASSIRVMESNYSGRQYIADHRGWFNPTGVTFIYPH
