VIOLIN: Vaccine Investigation and Online Information Network

pspK

General Information

Protegen ID

4158

Sequence Strain (Species/Organism)

Streptococcus pneumoniae

Taxonomy ID

1313

Other Database IDs

CDD:303028

Molecule Role

Protective antigen

Molecule Role Annotation

neutralization with purified recombinant PspK-R3 or rabbit anti-UD:R3 IgG inhibited binding of NESp to lung epithelial cells in vitro.(Jang et al., 2017)

References

Jang et al., 2017: Jang AY, Seo HS, Lin S, Chung GH, Kim HW, Lim S, Zhao L, Park IH, Lim JH, Kim KH. Molecular characterization of pneumococcal surface protein K, a potential pneumococcal vaccine antigen. Virulence. 2017; 8(6); 875-890. [PubMed: 28059611].

Gene Information

Gene Name

pspK

Protein Information

Protein Name

PspK

NCBI Protein GI

AEV46781

Protein pI

9.72

Protein Weight

64305.36

Protein Length

631

Protein Note

Uncharacterized protein conserved in bacteria (DUF2213); cl19842

Protein Sequence

>AEV46781.1 PspK [Streptococcus pneumoniae]
MNNKNIIPMSLASVAILATSFVANQPVTVKAEMASTASASSAVEQAKSKVAEAEKDVSKGQEIYDEAQKK
VQEKADVIRKIDEERQIINGEVQKAYLELRQAQEEKNKYPGRQEYTKKFDEANKKVDEITKKQKAKDEEY
TKKMYESIPDVGPLLTKLKAEKDKLAAAKRQLEKAKVAEKTEKEAKVKKLETELDQAREKVKKQAEEDKR
NYPTNTLKTLELEIAESYVKVKEAELELAKEEARELQDEDKFKQAKEKVESEKAEAKRLEELKTDRKKAA
EEAKRKAEEEAKRKAEEAKQKAEEAKRKAEEAKQKAEEEAKRKAEEEAKRKAEEEAKRKAEEEAKRKAEE
AKRKAEEEAKRKAEEEAKRKAEEEAKRKAEEAKRKAEEEAKRKAEEEAKRKAEEEAKRKAEEEAKRKAEE
EAKRKAEEEAKRKAEEAKRKAEEEAKRKAEEEAKRKAEEEAKRKAEEAKRKAEEEAKRKAEEEAKRKAEE
EAKRKAEEEAKRKAEEEAKRKAEEAKRKRVDSPVFAGTSLDNTYQAPAAKKGKQELPSTGAKDNVALASL
GFLGLFLGALPFVKHKN

Epitope Information

IEDB Linear Epitope