VIOLIN: Vaccine Investigation and Online Information Network

hlgB

General Information

Protegen ID

4171

Sequence Strain (Species/Organism)

Staphylococcus aureus

Taxonomy ID

1280

Other Database IDs

CDD:273388

Molecule Role

Protective antigen

Molecule Role Annotation

(Delfani et al., 2016)

References

Delfani et al., 2016: Delfani S, Mohabati Mobarez A, Imani Fooladi AA, Amani J, Emaneini M. Protection of mice against Staphylococcus aureus infection by a recombinant protein ClfA-IsdB-Hlg as a vaccine candidate. Medical microbiology and immunology. 2016; 205(1); 47-55. [PubMed: 26155981].

Gene Information

Gene Name

hlgB

Protein Information

Protein Name

gamma-hemolysin component C precursor, HlgB

NCBI Protein GI

AKB00489

Protein pI

9.81

Protein Weight

35450.76

Protein Length

411

Protein Note

beta-channel forming cytolysin; TIGR01002

Protein Sequence

>AKB00489.1 gamma-hemolysin component C precursor, HlgB [Staphylococcus aureus]
MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDK
SYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTL
GYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSF
HPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQI
RWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK

Epitope Information

IEDB Linear Epitope