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spa

General Information
Protegen ID 4174
Sequence Strain (Species/Organism) Staphylococcus aureus
Taxonomy ID 2
Other Database IDs CDD:309682
CDD:280394
CDD:331228
CDD:212030
Molecule Role Protective antigen
Molecule Role Annotation (Pozzi et al., 2015)
References
Pozzi et al., 2015: Pozzi C, Lofano G, Mancini F, Soldaini E, Speziale P, De Gregorio E, Rappuoli R, Bertholet S, Grandi G, Bagnoli F. Phagocyte subsets and lymphocyte clonal deletion behind ineffective immune response to Staphylococcus aureus. FEMS microbiology reviews. 2015; 39(5); 750-763. [PubMed: 25994610].
Gene Information
Gene Name spa
Protein Information
Protein Name immunoglobulin G-binding protein A
NCBI Protein GI WP_000728763
Protein pI 5.17
Protein Weight 55778.05
Protein Length 593
Protein Note YSIRK type signal peptide; pfam04650
Protein Sequence 
>WP_000728763.1 MULTISPECIES: immunoglobulin G-binding protein A [Bacteria]
MKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFYQVLNMPNLNADQRNGFIQSLKD
DPSQSANVLGEAQKLNDSQAPKADAQQNNFNKDQQSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVL
GEAKKLNESQAPKADNNFNKEQQNAFYEILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAP
KADNKFNKEQQNAFYEILHLPNLNEEQRNGFIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQN
AFYEILHLPNLTEEQRNGFIQSLKDDPSVSKEILAEAKKLNDAQAPKEEDNNKPGKEDNNKPGKEDNNKP
GKEDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDGNKPGKEDGNGVHVVKPG
DTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQALPETGEENPFIGTTVFG
GLSLALGAALLAGRRREL
Epitope Information
IEDB Linear Epitope