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esxA

General Information
Protegen ID 4176
Sequence Strain (Species/Organism) Staphylococcus aureus
Taxonomy ID 367830
Other Database IDs CDD:227179
Molecule Role Protective antigen
Molecule Role Annotation (Bagnoli et al., 2015)
References
Bagnoli et al., 2015: Bagnoli F, Fontana MR, Soldaini E, Mishra RP, Fiaschi L, Cartocci E, Nardi-Dei V, Ruggiero P, Nosari S, De Falco MG, Lofano G, Marchi S, Galletti B, Mariotti P, Bacconi M, Torre A, Maccari S, Scarselli M, Rinaudo CD, Inoshima N, Savino S, Mori E, Rossi-Paccani S, Baudner B, Pallaoro M, Swennen E, Petracca R, Brettoni C, Liberatori S, Norais N, Monaci E, Bubeck Wardenburg J, Schneewind O, O'Hagan DT, Valiante NM, Bensi G, Bertholet S, De Gregorio E, Rappuoli R, Grandi G. Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus. Proceedings of the National Academy of Sciences of the United States of America. 2015; 112(12); 3680-3685. [PubMed: 25775551].
Gene Information
Gene Name esxA
Protein Information
Protein Name ESAT-6 secretion system extracellular protein A
NCBI Protein GI A0A0H2XI99
Protein pI 4.34
Protein Weight 13241.094
Protein Length 225
Protein Note Ess extracellular protein A
Protein Sequence
>sp|A0A0H2XI99.1|ESXA_STAA3 RecName: Full=ESAT-6 secretion system extracellular protein A; Short=Ess extracellular protein A
MAMIKMSPEEIRAKSQSYGQGSDQIRQILSDLTRAQGEIAANWEGQAFSRFEEQFQQLSPKVEKFAQLLE
EIKQQLNSTADAVQEQDQQLSNNFGLQ

Epitope Information
IEDB Linear Epitope