VIOLIN: Vaccine Investigation and Online Information Network

clfB

General Information

Protegen ID

4183

Sequence Strain (Species/Organism)

Staphylococcus aureus

Taxonomy ID

46170

Other Database IDs

CDD:309682
CDD:313621
CDD:307064

Molecule Role

Protective antigen

Molecule Role Annotation

(Rauch et al., 2014)

References

Rauch et al., 2014: Rauch S, Gough P, Kim HK, Schneewind O, Missiakas D. Vaccine protection of leukopenic mice against Staphylococcus aureus bloodstream infection. Infection and immunity. 2014; 82(11); 4889-4898. [PubMed: 25183728].

Gene Information

Gene Name

clfB

Protein Information

Protein Name

Fibrinogen-binding protein B

NCBI Protein GI

SIN33476

Protein pI

3.66

Protein Weight

93865.65

Protein Length

1009

Protein Note

predicted cleavage at residue 45

Protein Sequence

>SIN33476.1 Fibrinogen-binding protein B [Staphylococcus aureus subsp. aureus]
MKKRIDYLSNKQNKYSIRRFTVGTTSVIVGATILFGIGNHQAQASEQSNDTTQSSKNNASADSEKNNMIE
TPQLNTTANDTSDISANTNSANVDSTTKPMSTQTSNTTTTEPASTNETPQPTAIKNQATAAKMQDQTVPQ
EANSQVDNKTTNDANSIATNSELKNSQTLDLPQSSPQTISNAQGTSKPSVRTRAVRSLAVAEPVVNAADA
KGTNVNDKVTASNFKLEKTTFDPNQSGNTFMAANFTVTDKVKSGDYFTAKLPDSLTGNGDVDYSNSNNTM
PIADIKSTNGDVVAKATYDILTKTYTFVFTDYVNNKENINGQFSLPLFTDRAKAPKSGTYDANINIADEM
FNNKITYNYSSPIAGIDKPNGANISSQIIGVDTASGQNTYKQTVFVNPKQRVLGNTWVYIKGYQDKIEES
SGKVSATDTKLRIFEVNDTSKLSDSYYADPNDSNLKEVTDQFKNRIYYEHPNVASIKFGDITKTYVVLVE
GHYDNTGKNLKTQVIQENVDPVTNRDYSIFGWNNENVVRYGGGSADGDSAVNPKDPTPGPPVDPEPSPDP
EPEPEPTPDPEPSPDPEPEPSPDPDPDSDSDSDSGSDSDSGSDSDSESDSDSDSDSDSDSDSDSESDSDS
ESDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSDSESDSESDSDSDSDSDSDSDSDSDSDSDS
DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
DSRVTPPNNEQKAPSNPKGEVNHSNKVSKQHKTDALPETGDKSENTNATLFGAMMALLGSLLLFRKRKQD
HKEKA

Epitope Information

IEDB Linear Epitope