lukS
General Information
Protegen ID
4186
Sequence Strain (Species/Organism)
Staphylococcus aureus
Taxonomy ID
1280
Other Database IDs
CDD:285242 GOA:Q53746 HSSP: 1PVL InterPro: IPR001340 InterPro: IPR003963 InterPro: IPR016183 UniProtKB/TrEMBL: Q53746
Molecule Role
Protective antigen
Molecule Role Annotation
(Karauzum et al. , 2013 )
References
Karauzum et al. , 2013: Karauzum H, Adhikari RP, Sarwar J, Devi VS, Abaandou L, Haudenschild C, Mahmoudieh M, Boroun AR, Vu H, Nguyen T, Warfield KL, Shulenin S, Aman MJ. Structurally designed attenuated subunit vaccines for S. aureus LukS-PV and LukF-PV confer protection in a mouse bacteremia model. PloS one . 2013; 8(6); e65384. [PubMed: 23762356 ].
Gene Information
Gene Name
lukS
Protein Information
Protein Name
leucocidin S
NCBI Protein GI
CAA51251
Protein pI
9.34
Protein Weight
33903.95
Protein Length
359
Protein Note
Leukocidin/Hemolysin toxin family; pfam07968
Protein Sequence
>CAA51251.1 lukS [Staphylococcus aureus]
MVKKRLLAATLSLGIITPIATSFHESKADNNIENIGDCAEVVKRTEDTSCDKWGVTQNIQFDFVKDKKYN
KDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYN
IGGNFNSGPSTGGNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYK
PYSQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTTHYGNSYLE
GSRIHKAFVNRNYTVKYEVNWKTHEIKVKGHN
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
IEDB ID
Epitope
MHC restriction
Starting position
Ending position
IEDB ID
Epitope
Starting position
Ending position
MVKKRLLAATLSLGIITPIATSFHESKADNNIENIGDCAEVVKRTEDTSCDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGPSTGGNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPYSQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTTHYGNSYLEGSRIHKAFVNRNYTVKYEVNWKTHEIKVKGHN