VIOLIN: Vaccine Investigation and Online Information Network

lukF

General Information

Protegen ID

4187

Sequence Strain (Species/Organism)

Staphylococcus aureus

Taxonomy ID

1280

Other Database IDs

CDD:273388

Molecule Role

Protective antigen

Molecule Role Annotation

(Karauzum et al., 2013)

References

Karauzum et al., 2013: Karauzum H, Adhikari RP, Sarwar J, Devi VS, Abaandou L, Haudenschild C, Mahmoudieh M, Boroun AR, Vu H, Nguyen T, Warfield KL, Shulenin S, Aman MJ. Structurally designed attenuated subunit vaccines for S. aureus LukS-PV and LukF-PV confer protection in a mouse bacteremia model. PloS one. 2013; 8(6); e65384. [PubMed: 23762356].

Gene Information

Gene Name

lukF

Protein Information

Protein Name

leukotoxin LukF

NCBI Protein GI

CRL36945

Protein pI

9.51

Protein Weight

36115.25

Protein Length

385

Protein Note

beta-channel forming cytolysin; TIGR01002

Protein Sequence

>CRL36945.1 leukotoxin LukF [Staphylococcus aureus]
MKMKKLVKSSIASSIALILLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDNDKLNLSQILIFNFIKDK
SYDKDTLILKAAGNINSGYKKPNPKDYNYSHFYWGGKYNVSISSESNENVNVVDYAPKNQNEEFQVQQTL
GYSYGGDINISNGLSGGGNGSKSFSETINYKQESYRTTIDRKTNHKFIGWGVEAHKIMNNGWGPYGRDSH
EDTYGNELFLGSRQSSSNAGQNFMPTHQMPLLSRGNFNPEFISVLSHKQNDTKKSKIKVTYQREMDRYTN
QWNGLHWIGNNYKNQNTVTFTSTYEVDWQNHSVKLLGTDSKETNPGV

Epitope Information

IEDB Linear Epitope