VIOLIN: Vaccine Investigation and Online Information Network

scpA_4

General Information

Protegen ID

4217

Sequence Strain (Species/Organism)

Streptococcus agalactiae

Taxonomy ID

1311

Other Database IDs

CDD:282500
CDD:173801
CDD:278510
CDD:239048
CDD:283851

Molecule Role

Protective antigen

Molecule Role Annotation

(Santillan et al., 2011)

References

Santillan et al., 2011: Santillan DA, Rai KK, Santillan MK, Krishnamachari Y, Salem AK, Hunter SK. Efficacy of polymeric encapsulated C5a peptidase-based group B streptococcus vaccines in a murine model. American journal of obstetrics and gynecology. 2011; 205(3); 249.e1-8. [PubMed: 21802065].

Gene Information

Gene Name

scpA_4

Protein Information

Protein Name

C5a peptidase precursor

NCBI Protein GI

AMQ15511

Protein pI

8.96

Protein Weight

72430.19

Protein Length

796

Protein Note

predicted cleavage at residue 36

Protein Sequence

>AMQ15511.1 C5a peptidase precursor [Streptococcus agalactiae]
MNTKQRFSIRKYKLGAVSVLLGTLFFLGGITNVAADSVINKPSDIAVEQQVKDSPTSIANETPTNNTSSA
LASTAQDNLVTKANNNSPTETQPVAESHSQATETFSPAANQPVESTQEVSKTPLTKQNLAVKPTPAISKE
TPQNIDSNKIITVPKVWNTGYKGEGTVVAIIDSGLDTNHDALQLNDSTKAKYQNEQQMNAAKAKAGINYG
KWYNNKVIFGHNYVDVNTELKEVKSTSHGMHVTSIATANPSKKDTNELIYGVAPEAQVMFMRVFSDEKRG
TGPALYVKAIEDAVKLGADSINLSLGGANGSLVNADDRLIKALEMARLAGVSVVIAAGNDGTFGSGASKP
SALYPDYGLIGSPSTAREAISVASYNNTTLVNKVFNIIGLENNKNLNNGLAAYADPKVSDKTFEVGKQYD
YVFVGKGNDNDYKDKTLNGKIALIERGDITFTKKVVNAINHGAVGAIIFNNKAGEANLTMSLDPEASTIP
AIFTQKEFGDVLAQKSYKIVFNNIKNKQANPNAGVLSDFSSWGLTADGQLKPDLSAPGGSIYAAINDNEY
DMMSGTSMASPHVAGATALVKQYLLKEHPELKKGDIERTVKYLLMSTAKAHLNKDTGAYTSPRQQGAGII
DVAAAVQTGLYLTGGENNYGSVTLGNIKDKISFDVTVHNINKVAKDLHYTTYLNTDQVKDGFVTLAPQQL
VHLQGKRYGLNQGKLKRLQLI

Epitope Information

IEDB Linear Epitope