c2II
General Information
Protegen ID
4231
Sequence Strain (Species/Organism)
Clostridium botulinum
Taxonomy ID
36828
Other Database IDs
CDD:214807
Molecule Role
Protective antigen
Molecule Role Annotation
(Prisilla et al. , 2016 )
References
Prisilla et al. , 2016: Prisilla A, Prathiviraj R, Sasikala R, Chellapandi P. Structural constraints-based evaluation of immunogenic avirulent toxins from Clostridium botulinum C2 and C3 toxins as subunit vaccines. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases . 2016; 44; 17-27. [PubMed: 27320793 ].
Gene Information
Gene Name
c2II
Protein Information
Protein Name
C2II
NCBI Protein GI
ADD91306
Protein pI
5.53
Protein Weight
92335.76
Protein Length
907
Protein Note
domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; smart00758
Protein Sequence
>ADD91306.1 C2II [Clostridium botulinum C]
MLVSKFENSVKNSNKNYFTINGLMGYYFENDFFNLNIISPTLDGNLTFSKEDINSILGNKIIKSARWIGL
IKPSITGEYILSTNSPNCRVELNGEIFNLSLNTSNTVNLIQGNVYDIRIEQLMSENQLLKNYEGIKLYWE
TSDIIKEIIPSEVLLKPNYSNTNEKSKFIPNNTLFSNAKLKANANRDTDRDGIPDEWEINGYTVMNQKAV
AWDDKFAANGYKKYVSNPFKPCTANDPYTDFEKVSGQIDPSVSMVARDPMISAYPIVGVQMERLVVSKSE
TITGDSTKSMSKSTSHSSTNINTVGAEVSGSLQLAGGIFPVFSMSASANYSHTWQNTSTVDDTTGESFSQ
GLSINTAESAYINPNIRYYNTGTAPVYNVTPTTTIVIDKQSVATIKGQESLIGDYLNPGGTYPIIGEPPM
ALNTMDQFSSRLIPINYNQLKSIDNGGTVMLSTSQFTGNFAKYNSNGNLVTDGNNWGPYLGTIKSTTASL
TLSLPDQTTQVAVVAPNFSDPEDKTPRLTLEQALVKAFRLEKKNGKFYFHGMEISANQKIQVFLDRNTNV
DFENQLKNTANKDIMNCIIKRNMNILVKVITFKENISSINIINDTNFGVESMTGLSKRIKGNDGIYRAST
KSFSFKSKEIKYPEGFYRMRFVIQSYEPFTCNFKLFNNLIYSNSFDIGYYDEFFYFYYNGSKSFFDISCD
IINSINRLSGVFLIELDKLINDIDHISSINIMNNTNSGIDYTTGLSNRIKGSDGIYRAETKAFSFRTKEI
NYSRGYYRIRFVVQCSSSFTCNFQLFNNQIFSRSFHEGFFDEFAYFKYDGNNSFLDISCNIISNSNPGVF
LIEVTRIGDL
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
IEDB ID
Epitope
MHC restriction
Starting position
Ending position
IEDB ID
Epitope
Starting position
Ending position
42088 MLVSKFENSVKNSNKNYFTINGLMGYYFENDFFNLNIISPTLDGNLTFSKEDINSILGNKIIKSARWIGLIKPSITGEYILSTNSPNCRVELNGEIFNLSLNTSNTVNLIQGNVYDIRIEQLMSENQLLKNYEGIKLYWETSDIIKEIIPSEVLLKPNYSNTNEKSKFIPNNTLFSNAKLKANANRDTDRDGIPDEWEINGYTVMNQKAVAWDDKFAANGYKKYVSNPFKPCTANDPYTDFEKVSGQIDPSVSMVARDPMISAY
1
265
3229 ANANRDTDRDGIPDE
182
197
914374 IGDYL
402
407
MLVSKFENSVKNSNKNYFTINGLMGYYFENDFFNLNIISPTLDGNLTFSKEDINSILGNKIIKSARWIGLIKPSITGEYILSTNSPNCRVELNGEIFNLSLNTSNTVNLIQGNVYDIRIEQLMSENQLLKNYEGIKLYWETSDIIKEIIPSEVLLKPNYSNTNEKSKFIPNNTLFSNAKLKANANRDTDRDGIPDEWEINGYTVMNQKAVAWDDKFAANGYKKYVSNPFKPCTANDPYTDFEKVSGQIDPSVSMVARDPMISAYPIVGVQMERLVVSKSETITGDSTKSMSKSTSHSSTNINTVGAEVSGSLQLAGGIFPVFSMSASANYSHTWQNTSTVDDTTGESFSQGLSINTAESAYINPNIRYYNTGTAPVYNVTPTTTIVIDKQSVATIKGQESLIGDYLNPGGTYPIIGEPPMALNTMDQFSSRLIPINYNQLKSIDNGGTVMLSTSQFTGNFAKYNSNGNLVTDGNNWGPYLGTIKSTTASLTLSLPDQTTQVAVVAPNFSDPEDKTPRLTLEQALVKAFRLEKKNGKFYFHGMEISANQKIQVFLDRNTNVDFENQLKNTANKDIMNCIIKRNMNILVKVITFKENISSINIINDTNFGVESMTGLSKRIKGNDGIYRASTKSFSFKSKEIKYPEGFYRMRFVIQSYEPFTCNFKLFNNLIYSNSFDIGYYDEFFYFYYNGSKSFFDISCDIINSINRLSGVFLIELDKLINDIDHISSINIMNNTNSGIDYTTGLSNRIKGSDGIYRAETKAFSFRTKEINYSRGYYRIRFVVQCSSSFTCNFQLFNNQIFSRSFHEGFFDEFAYFKYDGNNSFLDISCNIISNSNPGVFLIEVTRIGDL
