omp1
General Information
Protegen ID
425
Sequence Strain (Species/Organism)
Chlamydophila abortus
VO ID
VO_0010881
Taxonomy ID
83555
Other Database IDs
CDD:279628IPR000604 P16567
Molecule Role
Protective antigen
Molecule Role Annotation
The MOMP (omp1) DNA immunization induced a non-specific and partial protection in OF1 outbred mice fetuses against challenge with C. abortus (Héchard et al. , 2003 ).
Related Vaccines(s)
C. abortus DNA vaccine encoding MOMP
References
Héchard et al. , 2003: Héchard C, Grépinet O, Rodolakis A. Evaluation of protection against Chlamydophila abortus challenge after DNA immunization with the major outer-membrane protein-encoding gene in pregnant and non-pregnant mice. Journal of medical microbiology . 2003; 52(Pt 1); 35-40. [PubMed: 12488563 ].
Gene Information
Gene Name
omp1
Protein Information
Protein Name
major outer membrane protein
NCBI Protein GI
40601
Protein pI
7.65
Protein Weight
40147.34
Protein Length
457
Protein Note
submitted as Chlamydia psittaci;
Protein Sequence
>CAA36152.1 major outer membrane protein [Chlamydia abortus]
MKKLLKSALLFAATGSALSLQALPVGNPAEPSLLIDGTMWEGASGDPCDPCSTWCDAISIRAGYYGDYVF
DRVLKVDVNKTITGMGAVPTGTAAANYKTPTDRPNIAYGKHLQDAEWFTNAAFLALNIWDRFDIFCTLGA
SNGYFKASSAAFNLVGLIGVKGSSIAADQLPNVGITQGIVEFYTDTTFSWSVGARGALWECGCATLGAEF
QYAQSNPKIEMLNVVSSPAQFVVHKPRGYKGTAFPLPLTAGTDQATDTKSATIKYHEWQVGLALSYRLNM
LVPYISVNWSRATFDADAIRIAQPKLAAAVLNLTTWNPTLLGEATALDTSNKFADFLQIASIQINKMKSR
KACGVAVGATLIDADKWSITGEARLINERAAHMNAQFRF
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
IEDB ID
Epitope
MHC restriction
Starting position
Ending position
874705 PVGNPAEPS
24
33
IEDB ID
Epitope
Starting position
Ending position
58440 SIAADQLP
164
172
29059 ITQGIVEF
175
183
23021 GVKGSSIA
159
167
38606 LPNVGITQ
170
178
65852 TQGIVEFY
176
184
10486 DTSNKFAD
328
336
36085 LGEATALD
321
329
45495 NPTLLGEA
317
325
49703 PTLLGEAT
318
326
38273 LNLTTWNPTLLG
311
323
37325 LLGEATAL
320
328
2486 ALDTSNKF
326
334
35312 LDTSNKFA
327
335
19212 GEATALDT
322
330
4884 ATALDTSN
324
332
44489 NKFADFLQ
331
339
30691 KFADFLQI
332
340
5442 AVLNLTTW
309
317
51473 QLPNVGIT
169
177
48716 PNVGITQG
171
179
31064 KGSSIAAD
161
169
9871 DQLPNVGI
168
176
38272 LNLTTWNP
311
319
44907 NLTTWNPT
312
320
54125 RIAQPKLA
300
308
50887 QGIVEFYT
177
185
20919 GLIGVKGS
156
164
22508 GSSIAADQ
162
170
61078 SSIAADQL
163
171
26339 IGVKGSSI
158
166
25217 IAADQLPN
165
173
68690 VGITQGIV
173
181
29251 IVEFYTDT
179
187
31743 KLAAAVLN
305
313
66914 TTWNPTLL
314
322
67284 TWNPTLLG
315
323
51861 QPKLAAAV
303
311
40369 LVGLIGVK
154
162
20473 GIVEFYTD
178
186
51474 QLPNVGITQGIV
169
181
40217 LTTWNPTL
313
321
28315 IRIAQPKL
299
307
4885 ATALDTSNKFADFLQI
324
340
64905 TLLGEATA
319
327
69666 VLNLTTWN
310
318
48099 PKLAAAVL
304
312
20464 GITQGIVE
174
182
72903 WNPTLLGE
316
324
65 AAAVLNLT
307
315
66340 TSNKFADF
329
337
15146 FADFLQIA
333
341
755 ADQLPNVG
167
175
96 AADQLPNV
166
174
11199 EATALDTS
323
331
62907 TALDTSNK
325
333
493 AAVLNLTT
308
316
69233 VKGSSIAA
160
168
46382 NVGITQGI
172
180
59854 SNKFADFL
330
338
25395 IAQPKLAA
301
309
34656 LAAAVLNL
306
314
494 AAVLNLTTWNPTLL
308
322
49645 PTGTAAANYKTP
89
101
22509 GSSIAADQLP
162
172
36543 LIGVKGSS
157
165
4031 AQPKLAAA
302
310
737291 LWECGCATLGAEFQY
198
213
737233 LPVGNPAEPSLLIDG
23
38
737856 TTFSWSVGARGALWE
186
201
753403 NLVGLIGVKGSSIAADQLPNVGIT
153
177
753360 GVKGSSIAADQLPNV
159
174
780329 PTGTAAANYKTPTDRP
89
105
68716 VGLIGVKG
155
163
874705 PVGNPAEPS
24
33
919852 AQPKLAAAVLNLTTWNPTLLGEATALDTSNKFADFLQIAS
302
342
923576 NVVSSPAQFVVHKPRGYKGTAFPLPLTAGTDQATDTKSAT
223
263
923209 AVLNLTTWNPTLLGEA
309
325
923454 KWSITGEARLINERAAHMNAQFRF
366
390
MKKLLKSALLFAATGSALSLQALPVGNPAEPSLLIDGTMWEGASGDPCDPCSTWCDAISIRAGYYGDYVFDRVLKVDVNKTITGMGAVPTGTAAANYKTPTDRPNIAYGKHLQDAEWFTNAAFLALNIWDRFDIFCTLGASNGYFKASSAAFNLVGLIGVKGSSIAADQLPNVGITQGIVEFYTDTTFSWSVGARGALWECGCATLGAEFQYAQSNPKIEMLNVVSSPAQFVVHKPRGYKGTAFPLPLTAGTDQATDTKSATIKYHEWQVGLALSYRLNMLVPYISVNWSRATFDADAIRIAQPKLAAAVLNLTTWNPTLLGEATALDTSNKFADFLQIASIQINKMKSRKACGVAVGATLIDADKWSITGEARLINERAAHMNAQFRF
