VIOLIN: Vaccine Investigation and Online Information Network

VP2

General Information

Protegen ID

4254

Sequence Strain (Species/Organism)

Bluetongue virus

Taxonomy ID

40051

Other Database IDs

CDD:279269

Molecule Role

Protective antigen

Molecule Role Annotation

(Legisa et al., 2015)

References

Legisa et al., 2015: Legisa DM, Perez Aguirreburualde MS, Gonzalez FN, Marin-Lopez A, Ruiz V, Wigdorovitz A, Martinez-Escribano JA, Ortego J, Dus Santos MJ. An experimental subunit vaccine based on Bluetongue virus 4 VP2 protein fused to an antigen-presenting cells single chain antibody elicits cellular and humoral immune responses in cattle, guinea pigs and IFNAR(-/-) mice. Vaccine. 2015; 33(22); 2614-2619. [PubMed: 25858859].

Gene Information

Gene Name

VP2

Protein Information

Protein Name

VP2

NCBI Protein GI

AGS78451

Protein pI

6.92

Protein Weight

77652.84

Protein Length

750

Protein Note

Orbivirus outer capsid protein VP2; pfam00898

Protein Sequence

>AGS78451.1 VP2, partial [Bluetongue virus]
MDGLGIPIYKQGFPEHLLHGYEFTIDSSTKIQSVGGRHDVTKLPEMNAYDIKAESIRTALWYNPVRNDGF
VLPRVLDITLRGYDGKRAVIDSSKHKIFHTDERWVQWMMKDSMDAQPLKVGLDDRTQKIAHSLHNCVVKI
DSKKADTTSYHIEPIEDPSKGCLHTRAMLWNHLVRIEMSHAAQEIAYTLKPTYDIVVHAERRDRSQPFQP
GDQTLINFGRGQKVQMNHNSYEKMVEGLAHLVIRGKTPELIRDEIAKLDEICNRWIRSRHDPGEIKAYEL
CKILSTVGRKMLDQEKEPADEASLSIRFQEAIDNKFRQHDPERLKIFEHRNQRRDEDRFYILLMIAASDT
FNTRIWWSNPYPCLRGTLMASETKLGDVYSMIRSWYDWSVRPTYTPYEKSREQEKYIYGRVNLFDYVAEP
GTKIIHWEYKLNQQTKDITYEQGNPCDLFPDDDEAIVTKFDDVAYGQMVSDLINGGWDQERFKMHKILKS
QGNVLTIDFEKDAKLTSNEGVTMPEYFDKWIIAPMFNAKLRIKHSEIAQRRNDDPMVKRTLSPIAFDPIV
LQRLTLARYYDIRPAIMGQALSRQQGQSTYDEEVSKIEGYAEILQRRGIVQIPKKPCPTVTAQYTLERYA
LFLINILEQHVIQSTDEDVIYSHPRVDYKLEIYGESIVDISQIVIFVFDFLFERRRTVRGVYESR

Epitope Information

IEDB Linear Epitope