VIOLIN: Vaccine Investigation and Online Information Network

dnaK

General Information

Protegen ID

426

Sequence Strain (Species/Organism)

Chlamydophila abortus

VO ID

VO_0010882

Taxonomy ID

83555

Other Database IDs

CDD:234715

Molecule Role

Protective antigen

Molecule Role Annotation

In pregnant mice, the dnaK vaccine induced a non-specific partial protection from abortion after challenge with Chlamydophila abortus (Héchard et al., 2002).

Related Vaccines(s)

C. abortus DNA vaccine encoding DnaK

References

HÃ©chard et al., 2002: HÃ©chard C, GrÃ©pinet O, Rodolakis A. Protection evaluation against Chlamydophila abortus challenge by DNA vaccination with a dnaK-encoding plasmid in pregnant and non-pregnant mice. Veterinary research. 2002; 33(3); 313-326. [PubMed: 12056482].

Gene Information

Gene Name

dnaK

Protein Information

Protein Name

DnaK

NCBI Protein GI

26006347

Protein pI

4.71

Protein Weight

67356.62

Protein Length

707

Protein Note

molecular chaperone DnaK; Provisional; PRK00290

Protein Sequence

>AAN77259.1 DnaK [Chlamydia abortus]
MSEQKKSSKIIGIDLGTTNSCVSVMEGGQAKVIVSSEGTRTTPSIVAFKGNETLVGIPAKRQAVTNPAKT
LASTKRFIGRKYSEVESEIKTVPYQVASGSNGDVVFPIDGKQFTPEEIGAQVLIKMKETAEAYLGEPVTE
AVITVPAYFNDSQRASTKDAGRIAGLDVKRIIPEPTAAALAYGIDKAGDKKIAVFDLGGGTFDISILEIG
DGVFEVLSTNGDTHLGGDDFDEVIIKWMIEEFQKQEGIDLSKDNMALQRLKDAAEKAKIELSGMSSTEIN
QPFITMDANGPKHLTLTLTRAHFEKLASNLIERTKAPCQKALADAKLSASDIDDVLLVGGMSRMPAVQEV
VKSIFGKEPNKGVNPDEVVAIGAAIQGGVLGGEVKDVLLLDVIPLSLGIETLGGVMTPLVERNTTIPTQK
KQIFSTAADNQPAVTIVVLQGERPMAKDNKEIGRFDLTDIPPAPRGHPQIEVTFDIDANGILHVSAKDAA
SGREQKIRIEASSGLKEDEIQRMINDAEKNKEEDKKRREASDVRNEADSMIFRAEKAISDYKENIPESLT
KEIEERIEKVRSALKEDAPTEKIKEASDELSRHMQKIGEAMQSQSASAAANAQDGPNINTEDLKKHSFST
KPPTGNSSSSANNENIEEADVEIVDKPND

Epitope Information

IEDB Linear Epitope