VIOLIN: Vaccine Investigation and Online Information Network

E2

General Information

Protegen ID

4267

Sequence Strain (Species/Organism)

Human Papillomavirus

Taxonomy ID

10566

Other Database IDs

CDD:278909
CDD:317681
CDD:278912

Molecule Role

Protective antigen

Molecule Role Annotation

(Khan et al., 2017)

References

Khan et al., 2017: Khan S, Oosterhuis K, Wunderlich K, Bunnik EM, Bhaggoe M, Boedhoe S, Karia S, Steenbergen RDM, Bosch L, Serroyen J, Janssen S, Schuitemaker H, Vellinga J, Scheper G, Zahn R, Custers J. Development of a replication-deficient adenoviral vector-based vaccine candidate for the interception of HPV16- and HPV18-induced infections and disease. International journal of cancer. 2017; 141(2); 393-404. [PubMed: 28263390].

Gene Information

Gene Name

Protein Information

Protein Name

E2 protein

NCBI Protein GI

ATD50852

Protein pI

8.17

Protein Weight

43110.78

Protein Length

443

Protein Note

E2 (early) protein, N terminal; pfam00508

Protein Sequence

>ATD50852.1 E2 protein [Human papillomavirus]
MENRESLTDRFAALQENLMTLYERDPTDLYSQIQHWDLVKKENEYYYYARKEGMTSLGMFPAPALQVSEA
KAKQAIKMLILLKSLSKSQYASEIWRLRDTSVELVLQTEPKNCFKKGPFEVEVWFDKNPQKALPYPNWQW
IYYQDQNDVWHKVKGAADYNGTYYEEVTGDRVYFALFDSEAARYGESGQWLVKYNNEIICASVSSSSRCS
YDSSNERGPSSSSIYQPETGRQSEEVSHSETRPTSTSNLRRRRGGEQGEPTTSGGAKRRRADSGGGAPSP
EEVGGTHRSVERRHLSRLGLLQAEARDPPIALITGCANSLKCWRRRTKHKYSELFLDFSTNWTWVGDKVD
NNYQSKMLIAFSSLTQREAFVKTVNLPKGATLVYGQLNSL

Epitope Information

IEDB Linear Epitope