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E6 HPV 18

General Information
Protegen ID 4268
Sequence Strain (Species/Organism) Human Papillomavirus
Taxonomy ID 333761
Other Database IDs CDD:332494
Molecule Role Protective antigen
Molecule Role Annotation (Khan et al., 2017)
Related Vaccines(s) MEDI0457
References
Khan et al., 2017: Khan S, Oosterhuis K, Wunderlich K, Bunnik EM, Bhaggoe M, Boedhoe S, Karia S, Steenbergen RDM, Bosch L, Serroyen J, Janssen S, Schuitemaker H, Vellinga J, Scheper G, Zahn R, Custers J. Development of a replication-deficient adenoviral vector-based vaccine candidate for the interception of HPV16- and HPV18-induced infections and disease. International journal of cancer. 2017; 141(2); 393-404. [PubMed: 28263390].
Gene Information
Gene Name E6 HPV 18
Protein Information
Protein Name E6 protein
NCBI Protein GI AAP20594
Protein pI 8.56
Protein Weight 18681.84
Protein Length 216
Protein Note Early Protein (E6); cl27673
Protein Sequence
>AAP20594.1 E6 protein [Human papillomavirus type 18]
MARFEDPTRRPYKLPDLCTELNTSLQDIEITCVYCKTVLELTEVFEFAFKDLFVVYRDSIPHAACHKCID
FYSRIRELRHYSDSVYGDTLEKLTNTGLYNLLIRCLRCQKPLNPAEKLRHLNEKRRFHNIAGHYRGQCHS
CCNRARQERLQRRRETQV

Epitope Information
IEDB Linear Epitope