VIOLIN: Vaccine Investigation and Online Information Network

E7 HPV 18

General Information

Protegen ID

4269

Sequence Strain (Species/Organism)

Human Papillomavirus

Taxonomy ID

333761

Other Database IDs

CDD:295537

Molecule Role

Protective antigen

Molecule Role Annotation

(Khan et al., 2017)

References

Khan et al., 2017: Khan S, Oosterhuis K, Wunderlich K, Bunnik EM, Bhaggoe M, Boedhoe S, Karia S, Steenbergen RDM, Bosch L, Serroyen J, Janssen S, Schuitemaker H, Vellinga J, Scheper G, Zahn R, Custers J. Development of a replication-deficient adenoviral vector-based vaccine candidate for the interception of HPV16- and HPV18-induced infections and disease. International journal of cancer. 2017; 141(2); 393-404. [PubMed: 28263390].

Gene Information

Gene Name

E7 HPV 18

Protein Information

Protein Name

E7 protein

NCBI Protein GI

AAP20595

Protein pI

4.48

Protein Weight

11905.36

Protein Length

162

Protein Note

E7 protein, Early protein; cl02891

Protein Sequence

>AAP20595.1 E7 protein [Human papillomavirus type 18]
MHGPKATLQDIVLHLEPQNEIPVDLLCHEQLSDSEEENDEIDGVNHQHLPARRAEPQRHTMLCMCCKCEA
RIELVVESSADDLRAFQQLFLNTLSFVCPWCASQQ

Epitope Information

IEDB Linear Epitope